1. The Chapter 5 Test will be on Thursday, October 16.

2. Sign up for your shirt number and size. ~ $23.00

3. We would use the same font for names which will be on the sleeve - do you want the name to read from shoulder to wrist?

4. Graph…..

5. Chapter 5 Bulk Transport Local and Long Distance Signaling

6. You Must Know Bulk Transport How cells communicate with each other.

7. CONCEPT 5.5: Bulk transport across the plasma membrane occurs by exocytosis and endocytosis Exocytosis © 2014 Pearson Education, Inc. Endocytosis

8. CONCEPT 5.6: The plasma membrane plays a key role in most cell signaling In multicellular organisms, cell-to-cell communication allows the cells of the body to coordinate their activities. Communication between cells is also essential for many unicellular organisms. © 2014 Pearson Education, Inc.

9. Local Signaling By Direct Contact

10. Plant Cells Local Signaling By Direct Contact

11. Local regulator diffuses through extracellular fluid. Secreting cell Secretory vesicle Target cell Local signaling Paracrine signaling © 2014 Pearson Education, Inc.

12. Target cell is stimulated. Electrical signal along nerve cell triggers release of neuro- transmitter. Neurotransmitter diffuses across synapse. Synaptic signaling Local signaling © 2014 Pearson Education, Inc.

13. Long-distance signaling Endocrine cell Target cell specifically binds hormone. Endocrine (hormonal) signaling Hormone travels in bloodstream. Blood vessel © 2014 Pearson Education, Inc.

14. The Three Stages of Cell Signaling: A Preview Cells receiving signals undergo three processes – Reception – Transduction – Response © 2014 Pearson Education, Inc.

15. Figure 5.20-1 EXTRACELLULAR FLUID Plasma membrane Reception Receptor Signaling molecule CYTOPLASM © 2014 Pearson Education, Inc.

16. Figure 5.20-2 EXTRACELLULAR FLUID CYTOPLASM Plasma membrane ReceptionTransduction Relay molecules Receptor Signaling molecule © 2014 Pearson Education, Inc.

17. Figure 5.20-3 EXTRACELLULAR FLUID CYTOPLASM Plasma membrane Response ReceptionTransduction Relay molecules Activation Receptor Signaling molecule © 2014 Pearson Education, Inc.