1. Daniel Goldstein and Daniel Guobadia DNA Replication and Repair

2. Intro to DNA  DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms.  DNA is double stranded and the two stands form a spiral called a double helix.  DNA replication is possible because the strands of the double helix are complementary and if you have one you can rebuild the other.  DNA replication occurs in the cytoplasm of prokaryotes and in the nucleus of eukaryotes.  DNA replication occurs before cell division because the parent cell needs to pass the genetic information on to its daughter cells.  DNA replication is used for cell reproduction, mitosis, or gamete production, meiosis.

3. DNA Replication The DNA strands are first split in two by helicase. DNA polymerase III is bound by a primer and adds corresponding bases from the leading strand. Okazaki fragments separated by primers are formed for the lagging strand, and are later connected by ligase. DNA polymerase I does proofreading after every base pair is added. Mismatch repair makes more corrections after replication.

4. Number the Steps! ___A primer binds DNA polymerase III binds to the DNA ___Okazaki fragments are added ___Proofreading ___DNA is unwound by helicase ___DNA polymerase III adds corresponding base pairs ___Okazaki fragments are joined together by ligase ___Mismatch repair