1. Chapter 25: Reproduction and Development From two parents to one embryo to one baby Lecture by Jennifer Lange, Chabot College; Clicker questions by Kris Curran, University of Wisconsin-Whitewater

3. 25.1 Reproductive options (and ethical issues) are on the rise. The more we know about how it works, the more complicated it becomes.

4. Take-home message 25.1  Technology is making conception and pregnancy possible in many situations where previously they were not possible.  But it is simultaneously giving rise to complex legal battles and ethical dilemmas.

5. 25.2 There are costs and benefits to having a partner: asexual versus sexual reproduction.

6. Reproduction without Sex

7. Sex = Gametes Merging

8. Neither Method is Perfect

9. Which answer below is an example of asexual reproduction by fragmentation? 1.Planaria literally rip themselves apart and regenerate the missing pieces. 2.Unfertilized eggs of bees develop into drones. 3.Certain species of yeast form a small bud on the side of the cell that grows bigger and finally separates from the parent cell. 4.Copulation between a male and female cat.

10. Take-home message 25.2  Organisms can reproduce in two ways: asexually or sexually, or both.  Each has advantages and disadvantages, depending on the organism’s environment.

11. 25.3 Fertilization can occur inside or outside a female’s body.

12. Fertilization in animals requires a watery environment, which can be found either inside or outside of the organism.

13. Embryonic Nourishment and Protection—Oviparity

14. Embryonic Nourishment and Protection— Ovoviviparity

15. Embryonic Nourishment and Protection— Viviparity

16. Oviparity, ovoviviparity, and viviparity are all strategies for providing: 1.a moist environment for embryonic development. 2.a safe place for embryonic development. 3.a source of nutrients for embryonic development. 4.the environment necessary for fertilization to occur.

17. Take-home message 25.3  Sexual reproduction requires fertilization, which can happen externally or internally.  Among those species having internal fertilization, development of the embryo can be nourished by yolk or by nutrients in the mother’s blood.

19. 25.4 Sperm are made in the testes.

20. Male Reproductive Organs The male organs are specialized for gamete production and delivery.

21. After puberty, sperm are constantly produced in the testis by meiosis.

22. Sperm: motile gametes

24. Which organ is a place where sperm mature and are stored before ejaculation? 1.Vas deferens 2.Prostate 3.Testis 4.Epididymis 5.Penis

25. Take-home message 25.4  In adult men, sperm are continuously produced in the testes by meiosis.  Semen—consisting of sperm cells and fluids that nurture and aid the sperm in fertilization—is ejaculated during copulation.

26. 25.5 There is unseen conflict among sperm cells. A male’s sperm must compete with each other, and possibly with those of other males, in order to fertilize an egg. Thus, strategies have evolved to enhance success.

28. If a female mates with multiple males, which adaptation would increase one male’s chances of fertilizing an ovum? 1.Produce more sperm than the other males 2.Block other male’s sperm from entering the female 3.Remove other male’s sperm from the female 4.All of the above

29. Take-home message 25.5  When females mate with more than one male, sperm competition occurs and can lead to a variety of adaptations that aid in the displacement of rival males’ sperm.

30. 25.6 Eggs are made in the ovaries (and the process can take decades).

31. Female Reproductive Organs The organs of the female are specialized for receiving sperm and nourishing a growing fetus.

33. Meiosis usually produces four haploid cells. Why do oogonia in females only produce one haploid ovum? 1.Cytoplasm is lost between meiosis I and II. 2.Extra chromosomes are lost via formation of polar bodies in meiosis I and II. 3.Extra chromosomes are degraded during meiosis II. 4.Cytoplasm is retained in the polar bodies.

34. Take-home message 25.6  Genetically, egg production and sperm production are similar, with both producing variable haploid gametes.  In the ovaries, diploid cells begin to undergo meiosis, a process that continues in the Fallopian tubes following ovulation.  A much smaller number of eggs than sperm are produced, however, and each egg is considerably larger than a sperm cell.

35. 25.7 Hormones direct the process of ovulation and the preparation for gestation.

36. The ovarian cycle and menstrual cycle are coordinated by hormones produced in the pituitary gland and in the ovary itself.

37. Two Fates of an Egg Fertilized or Not Fertilized

38. Which hormone is produced by the zygote and maintains the corpus luteum after fertilization? 1.Follicle stimulating hormone (FSH) 2.Luteinizing hormone (LH) 3.Human chorionic gonadotropin (HCG) 4.Estrogen

39. Take-home message 25.7  In the ovaries, a cell within a follicle is stimulated to develop into a fertile egg by coordinated secretions of the hormones estrogen, FSH, and LH.  The preparation of the uterus for implantation of a fertilized egg is coordinated by progesterone.

41. 25.8 In fertilization, two cells become one.

42. Sperm Penetrates Egg

43. The fusion of sperm and egg nuclei occurs in: 1.follicle cells. 2.zona pellucida. 3.egg cytoplasm. 4.fallopian tube.

44. Take-home message 25.8  At fertilization: a sperm penetrates the protective zone around the egg, the egg blocks additional sperm entry, and the sperm and egg membranes fuse.

45. Take-home message 25.8  The egg then completes its second meiotic division, and the haploid nuclei of the egg and sperm fuse, forming a diploid zygote.

46. 25.9 Numerous strategies can help prevent fertilization.

47. Contraception Strategies Birth control can intervene at multiple stages of the reproductive process to prevent pregnancy: 1. preventing ovulation 2. preventing fertilization 3. preventing implantation

48. Hormonal regulation can prevent the development and ovulation of an egg. Contraception Strategies

49. Barrier methods prevent the sperm and egg from meeting. Contraception Strategies

50. Preventing the implantation of a fertilized egg is accomplished by covering or losing the endometrium. Contraception Strategies

51. Low estrogen levels cause the pituitary to release FSH. Which birth control method blocks FSH release by the pituitary gland? 1.Birth control pills 2.Hormone implants 3.Morning after pills 4.RU 486 5.1 and 2 6.All of the above

52. Take-home message 25.9 Pregnancy can be prevented by numerous methods, each of which acts in one or more ways to prevent ovulation, fertilization, or implantation.

53. 25.10 Sexually transmitted diseases reveal battles between microbes and humans.

55. STDs are transmitted mostly via mucus secretion between sexual partners. Which birth control method would decrease the spread of STDs? 1.Birth control pills 2.IUD 3.Condom 4.Abstinence 5.3 and 4 6.All of the above

56. Take-home message 25.10  Sexually transmitted diseases (STDs) are caused by a variety of organisms, including bacteria viruses, protists, fungi, and arthropods.  Worldwide, more than 300 million people are infected each year.  The effects of being infected with an STD range from non-existent to mild to extreme discomfort, sterility, or even death.

58. 25.11 Early embryonic development occurs during cleavage, gastrulation, and neurulation.

59. Stages of Embryonic Development Embryonic development has three stages: 1.Cleavage: early cell division 2.Gastrulation: formation of three distinct germ layers 3.Neurulation: formation of early organ systems

60. Stages of Embryonic Development Cleavage: single cell divides by mitosis to form a hollow ball of approximately 1000 cells.

61. Stages of Embryonic Development Gastrulation: three distinct germ layers of tissue form.

62. Stages of Embryonic Development Neurulation: the three types of tissue created during gastrulation begin to develop into the various organs and tissues.

63. During which stage of early embryonic development do the three germ layers (ectoderm, endoderm, and mesoderm) form? 1.Cleavage 2.Gastrulation 3.Neurulation 4.Differentiation

64. Take-home message 25.11  Soon after fertilization, cleavage takes place and many rapid cell divisions occur without overall growth.  Following cleavage is gastrulation, in which three distinct germ layers with specific developmental fates form.  In neurulation, mesoderm forms a supporting rod called the notochord, and above that, an infolding of ectoderm forms a neural tube, which will become the brain and spinal cord.

65. 25.12 How does an embryo become male or female?

67. Take-home message 25.12  Mammalian embryos develop female internal and external reproductive organs unless a gene on the Y chromosome stimulates the fetal gonads to develop as testes, which then stimulates the development of male reproductive organs.

68. 25.13 There are three stages of pregnancy.

69. Stages of Pregnancy Trimester 1: differentiation of tissues, organ formation, implantation

70. Stages of Pregnancy The placenta forms from the outer layers of the blastocyst—the amnion and the chorion. The amnion becomes the fluid-filled amiontic sac. The chorion joins with the endometrium to form the placenta.

71. Stages of Pregnancy Trimesters 2 and 3: growing larger and maturing

72. What structure provides food, waste removal, and gas exchange for the developing embryo and fetus during pregnancy? 1.Uterus 2.Placenta 3.Amnion 4.Zona pellucida 5.Corpus luteum

73. Take-home message 25.13  The 9-month development of a human embryo and fetus is divided into three equal periods, or trimesters.  The first trimester is primarily a time of development and differentiation of cells and tissues as the embryo implants and the placenta forms.  The second and third trimesters are characterized mostly by significant growth and rapid development of the fetus’s nervous system.

74. 25.14 Pregnancy culminates in childbirth and the start of lactation.

75. Fetal hormones stimulate uterine contractions that dilate the cervix and push the fetus through the birth canal.

76. Hormones stimulate and coordinate lactation.

77. What hormone is involved in stimulating lactation? 1.Oxytocin 2.Human chorionic gonadotropin 3.Prolactin 4.Estrogen

78. Take-home message 25.14  Birth is the culmination of pregnancy and occurs in three phases. The first is the initiation of contractions and the dilation of the cervix. The second is delivery of the baby. The third is expulsion of the placenta.

79.  Lactation, stimulated by prolactin and other hormones, nourishes the baby with proteins, carbohydrates, and lipids and provides the infant with protective antibodies. Take-home message 25.14

81. Helping Sperm Meet Egg

82. If you were trying to conceive a baby using ART which procedure would you choose? Females: 1.IFT 2.ZIFT 3.GIFT Males: 4.IFT 5.ZIFT 6.GIFT

83. Classroom Catalyst Reproductive Technology and Human Cloning

84. Sheep, dogs, and endangered species have been cloned. Human cloning should also be allowed to occur. 1.Strongly agree 2.Agree 3.Neutral 4.Disagree 5.Strongly disagree

85. Take-home message 25.15  Assisted reproductive technology (ART) procedures typically involve removing eggs from a woman’s ovaries, combining them with sperm to achieve fertilization, and reinserting the fertilized eggs into the woman’s uterus or Fallopian tube.  These technologies can enable previously infertile couples to have babies.