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Published byAriel Watts Modified over 9 years ago
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Protein Synthesis
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The DNA Code It is a universal code. The order of bases along the DNA strand codes for the order in which amino acids are chemically joined together to form a polypeptide
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From DNA to Protein Protein synthesis involves two types of nucleic acids: DNA (deoxyribonucleic acid) RNA (ribonucleic acid)
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RNA RNA, like DNA, is a polymer formed by a sequence of nucleotides Three Types of RNA: messenger RNA (mRNA) transfer RNA (tRNA) ribosomal RNA (rRNA)
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Differences Between DNA and RNA DNARNA double-strandedsingle-stranded sugar = deoxyribosesugar = ribose bases = A,T,C,Gbases = A,U,C,G (uracil takes the place of thymine)
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Protein Synthesis involves two processes: 1.Transcription: the copying of the genetic message (DNA) into a molecule of mRNA 2.Translation: mRNA is used to assemble an amino acid sequence into a polypeptide
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A sequence of 3 bases called a codon codes for one amino acid
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Transcription occurs in the nucleus of the cell Steps in transcription 1)Initiation: DNA strand separates and serves as a template (pattern) for mRNA assembly. mRNA polymerase attaches to the template Strand of DNA.
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2) Elongation: RNA Polymerase attaches to the template strand of DNA. Free mRNA nucleotides match up to the exposed nucleotides on the DNA strand.
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3)Termination: mRNA strand separates from the DNA strand when a “stop codon” is reached and the entire gene has been transcribed. 4)the mRNA strand carries the code for the production of one polypeptide
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Translation occurs in the cytoplasm of the cell, at the ribosome Always begins with the mRNA codon AUG 1) Initiation: mRNA moves out of the nucleus and into the cytoplasm to a ribosome
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2) Elongation: mRNA is “read” by the ribosome as the anticodons of the tRNA molecules attach to their complementary condons on the mRNA molecules creating a chain of amino acids.
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3)Termination: mRNA molecule moves across the ribosome tRNA temporarily attaches to the mRNA strand. The amino acids are joined by a peptide bond by enzymes until a “stop” codon is reached
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tRNA Molecule
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4. a polypeptide is produced
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