1. MUSC RESEARCH OPERATIONS: NURTURING THE CULTURE OF DISCOVERY AND TRANSLATIONAL SCIENCES Stephen M. Lanier, Ph.D. FACULTY RESEARCH ORIENTATION Collaborative Services Supporting Science and Discovery August 9, 2011

2. NURTURING THE CULTURE OF DISCOVERY AND TRANSLATIONAL SCIENCE THE CHALLENGES CREATE AN ENVIRONMENT IN WHICH THE CREATIVE ABILITIES OF AN OFTEN DISPARATE GROUP OF HIGHLY TALENTED INDIVIDUALS CAN FLOURISH SUSTAINING OUR RESEARCH PROGRAMS IN THE FACE OF BUDGETARY PRESSURES AND INCREASED EXPENSE AND REGULATION THE GOAL - SEAMLESS RESEARCH SUPPORT

3. The Idea The Discovery Incubation and Nurturing Development Benefit for Society THE FLOW

4. Biomedical Research Growth Technology Development MUSC Strategic Plan INNOVATION THROUGH COLLABORATION

5. 1992199419961998200020022004200620082010 Biomedical Research Funding

6. NCI Designation – Hollings Cancer Center (~$6M) CTSA - South Carolina Clinical and Translational Research Institute (~$20M) NSF RII - Research Infrastructure Award - Tissue Biofabrication (~$20M) THREE TRANSFORMATIVE REGIONAL PROGRAM AWARDS (2009)

7. Brain ImagingBioengineering CancerDiagnostics Drug DiscoveryHealth Care Quality Health ITNeurosciences Regenerative MedicineTelemedicine http://www.sccoee.org/ 27 Biomedical Centers (64 Endowed Chairs)

8. DISCOVERY ENABLING TECH- NOLOGIES DEVELOP- MENT AND APPLICA- TION SC BIOMEDICAL RESEARCH INDUSTRY PARTNERS DRUG DISCOVERY, DIAGNOSTICS, MEDICAL DEVICES, BIOENGINEERING, HEALTH CARE TECHNOLOGY

9. Southeastern Virtual Institute for Health Equity and Wellness (SE VIEW) Department of Defense (3 year, $12.7 M.) SE VIEW supports 14 MUSC investigators focused on educational initiatives; preventive medicine; health and wellness programs; community partnerships and outreach; and research.

10. BIOTECH START UPS Bridge to Life CharlestonPharma Immunologix Iverson Genetic Diagnostics MitoHealth Neurological Testing Services VaxyGen Assay Services Vortex SCRA-MUSC INNOVATION CENTER

12. Collaborative Services Supporting Research and Discovery Research Operations Research Cores Grants & Contracts Accounting MUSC Library Vivarium Success Center and SCTR Research Development Scientific Editing Research Integrity and Regulatory Monitoring Research & Sponsored Programs Information Technology Technology Transfer University Development

13. Associate Provost for Research (Stephen M.Lanier, Ph.D.) University Compliance (Cynthia Teeter) Special Projects (Loretta Lynch-Reichert, M.S.) (Lynn M. Veatch, Ph.D.) Foundation for Research and Development (William. C. Hood, J.D.) Laboratory Animal Resources (Michael Swindle, D.V.M.) Administrative Coordinator (Robin Hanckel) Research Development (Joann Sullivan, Ph.D.) Office of Scientific Editing and Publications (Jennifer Schnellman, Ph.D.) Research & Sponsored Programs (Darren McCants) Research Operations Administration (Leslie Kendall) Research Integrity IRB IACUC IBC RIC (Kathryn Magruder, Ph.D.) Risk Management (Wayne Brannan) Grants and Accounting (Velma Stamp) Research Informatics (Michele Adelson) University Research Committee (Craig Beeson, Ph.D.) SCTR (Kathleen Brady, M.D., Ph.D.)

14. Associate Provost for Research Lanier Laboratory Office of Research Development Research and Sponsored Programs, Research Integrity (IRB, IACUC, IBC, RIC) Grants and Contract Accounting, Foundation for Research Development SCTR Research Operations Administration Office of Scientific Editing and Publications

21. The Lifecycle of a Grant/Award Conception of idea Search for Funding Proposal Creation Budget Creation Routing & Approval Submission To Sponsor Review by Sponsor Grant awarded Setting up Award by GCA Post Award Administration Award Close Out and Audit

22. Collaborative Services Supporting Research and Discovery Research Operations Research Cores Grants & Contracts Accounting MUSC Library Vivarium Success Center and SCTR Research Development Scientific Editing Research Integrity and Regulatory Monitoring Research & Sponsored Programs Information Technology Technology Transfer University Development