1. 1 Medical Informatics And Technology Application Consortium www.meditac.com Telemedicine and Assistive Technology Virginia Commonwealth University, MITAC Richmond Virginia Meditac.com Ronald Merrell, MD, FACS Azhar Rafiq, MD, MBA

2. 2 Medical Informatics And Technology Application Consortium www.meditac.com The Astronaut in a Hostile and Remote Environment  Apprehend the physiologic status  Collate the data  Interpret the data locally  Propose and realize a response  Record the event and transmit to a distant management site  Design, validate and implement sensor network for semi-autonomous physiological monitoring system.

3. 3 Medical Informatics And Technology Application Consortium www.meditac.com Analogies for Assistive Technology Requirements  Medical situations or probabilities that require prompt response and might otherwise confine the individual to a strictly monitored environment  Desire for maximal independence of mobility and location  Need for local prompt alert and response while maintaining strong connection to a distant management site  Great technical solutions for sensing, data management and telecommunications awaiting application

4. 4 Medical Informatics And Technology Application Consortium www.meditac.com Program Description Sensor network Data sampling and conditioning Data archive and analysis Data communication VPack Data pre-processing

5. 5 Medical Informatics And Technology Application Consortium www.meditac.com Sensor network  Skin Surface Temperature  Galvanic Skin conductance  Pulse Oximeter - Heart Rate  Pulse Oximeter - Oxygen Saturation (SpO2)  Plethysmograph – Blood Volume (Perfusion)

6. 6 Medical Informatics And Technology Application Consortium www.meditac.com Hab RV SCOUT CAI-1 CAI-2 SCOUT Camp Advanced EVA Desert RATS 2005 CAIpack

7. 7 Medical Informatics And Technology Application Consortium www.meditac.com Liquid cooling garment (overlay) Skin Temperature sensor Pulse oximetry sensor Physiological sensor network in direct contact with skin Integrate sensor signals into a single feed to computer with VPack All wires from sensors embedded inside sock to prevent tear in suit bladder Bio Sensor Network Galvanic Skin Resistance

8. 8 Medical Informatics And Technology Application Consortium www.meditac.com Data archive and analysis  ASCII file format with fixed column format  Date and time stamp  Data analysis algorithm  Alerts communication with text message to cell phone

9. 9 Medical Informatics And Technology Application Consortium www.meditac.com Data display interface

10. 10 Medical Informatics And Technology Application Consortium www.meditac.com Diabetes monitoring applications Chronic care- Diabetes monitoring Alarm - text message Demonstration b/w San Francisco and Virginia – Diabetes technology conference Software interface

11. 11 Medical Informatics And Technology Application Consortium www.meditac.com Passive Wireless Monitoring for Signs of Hypoglycemia Ronald C. Merrell, MD, FACS Virginia Commonwealth University Richmond, Virginia

12. 12 Medical Informatics And Technology Application Consortium www.meditac.com HYPOMON MEASURES EKG AND SKIN IMPEDANCE HypoMon ™

13. 13 Medical Informatics And Technology Application Consortium www.meditac.com

14. 14 Medical Informatics And Technology Application Consortium www.meditac.com Assistive Living Applications  Activity  Location  Vital signs  Acute change alarms  Trending alerts  Messaging to reconfirm regimen and refine response to changes

15. 15 Medical Informatics And Technology Application Consortium www.meditac.com Assistive Living Applications  Alzheimer Syndrome  Physical impairment due to neurological injury  Congestive heart failure monitoring  Diabetes mellitus monitoring  Arrhythmia monitoring  Sleep pathology  Fall alerts  Alerts for loss of consciousness  Seizure alerts  Monitoring for peripheral vascular disease  Home or out of home

16. 16 Medical Informatics And Technology Application Consortium www.meditac.com Thank you Our SBIR partners:  Sleepmate Inc  Carillion Health Systems  AFrame Inc  VCU Health System This presentation and a pertinent publication are available on our web site under presentations. ronald.merrell@vcu.edu