1. Vaccine Timeline A Look Through Time START

2. Instructions: For this assignment you will use the following timeline to answer questions 1 and 2. Before answering the questions, be sure to click on each year of the timeline. To answer question 3 you will need to find credible resources dealing with the topic on the internet. This assignment is to be turned in on paper. 1.Why is it possible to eliminate a disease like smallpox but not tetanus? 2.Compare Dr. RRK’s children’s immunization records which can be found within the timeline. For each child list the ages that they received the Hepatitis B vaccine as well as the Chicken Pox (Varicella) vaccine. What accounts for the differences you see in the ages they received them? Are there any vaccines that one child has that another doesn’t, and WHY? 3.Write a paragraph discussing the conditions surrounding the retraction of the Rotavirus vaccine from the market. Can you find specifics as to why the Rotavirus vaccine was initially sent out into the market and then later pulled? To Timeline

3. 1905 Smallpox 1796 1796 Smallpox 1879 Cholera 1881 Anthrax 1882 Rabies 1890 Tetanus Diphtheria 1897 Plague

4. 1926 Pertussis 1927 Tuberculosis 1935 Yellow Fever 1937 Typhus 1945 Influenza 1952 Polio

5. 1964 Measles 1967 Mumps 1970 Rubella 1974 Chicken Pox 1977 Pneumonia 1981 Hepatitis B 1972 Smallpox 1971 MMR

6. 1971 MMR (tri-valent measles/mumps/rubella) licensed.

7. 1972 U.S. ended routine use of smallpox vaccine See also 1796, 1905, 2003179619052003

8. 1992 Alex’s Immunization 1985 HiB 1997 Zach’s Immunization 1998 Rotavirus 1999 Rotavirus 2001 Katie’s Immunization 2003 Smallpox Today Immunization standards 1994 Max’s Immunization 1995 Chicken Pox Back to the start

9. 1995 Chicken Pox vaccine licensed and put into wide spread use. See also 19741974

10. 2003 Smallpox vaccine stored in emergency first responder med-kits.Smallpox See also 1796, 1905, 1972179619051972

11. 2001 Katie’s Immunization

13. 1999 Rotavirus vaccine pulled off market due to significant adverse reactions.

14. 1998 First vaccine for Rotavirus Structure of rotavirus obtained by electron cryomicroscopy and computer image processing. httphttp://www.bcm.tmc.edu/biochem/ biochem_images.htmlwww.bcm.tmc.edu/biochem/ biochem_images.html

15. 1994 Max’s immunization Max with baby Katie

17. 1997 Zach’s Immunizations

19. 1992 First vaccine for Hepatitis A Alex’s immunizations

21. 1985 First vaccine for Haemophilus influenzae B (HiB)

22. 1981 First vaccine for Hepatitis B

23. 1977 First vaccine for Pneumonia

24. 1974 First vaccine for Chicken Pox (Varicella) See also 19951995

25. 1970 First vaccine for Rubella

26. 1967 First vaccine for Mumps

27. 1964 First vaccine for Measles

28. 1952 First vaccine for Polio

29. 1945 First vaccine for Influenza

30. 1937 First vaccine for Typhus

31. 1935 First vaccine for Yellow Fever

32. 1927 First vaccine for Tuberculosis

33. 1926 First vaccine for Pertussis or the Whooping Cough

34. 1890 First vaccine for TetanusTetanus First vaccine for Diphtheria

35. Tetanus Tetanus is a disease caused by the toxin of the bacterium Clostridium tetani that affects the central nervous system, sometimes resulting in death. Spores of the bacterium Clostridium tetani live in the soil and are found around the world. In the spore form, C. tetani may remain dormant in the soil, and it can remain infectious for more than 40 years.

36. 1897 First vaccine for the Plague

37. 1882 First vaccine for Rabies

38. 1881 First vaccine for Anthrax

39. 1879 First vaccine for Cholera

40. 1796 Smallpox vaccine is created, the first vaccine for any disease.Smallpox See also 1905, 1972, 2003190519722003

41. 1905 In 1905 the US Supreme Court upholds state law mandating smallpox vaccinationssmallpox See also 1796, 1972, 2003179619722003

42. Smallpox Smallpox is a viral disease unique to humans. It is caused by the variola virus. To sustain itself, the virus must pass from person to person in a continuing chain of infection and is spread by inhalation of air droplets or aerosols.

44. References Smallpox information –http://www.bt.cdc.gov/agent/smallpox/overview/disease-facts.asp –http://www.cdc.gov/ncidod/EID/vol5no4/henderson.htm Tetanus information –http://www.uhseast.com/14545.cfm Vaccine timeline information –http://www.909shot.com/Timeline/timeline.htm –http://en.wikipedia.org/wiki/Timeline_of_vaccines Images –http://www.idph.state.il.us/about/vpcd.htm –Microsoft health clipart collection on-line