2. 

3. UMELISA  Birth defects Down syndrome Congenital hypothyroidism Phenylketonuria Biotinidase deficiency HIV 1+2 Hepatitis B Hepatitis C HTLV I +II Chagas disease Dengue Leprosy Tetanus Toxoplasmosis Allergy

4. 37 47 38 66 36 6 2 1 1

6. NATIONAL SCREENING AND OTHER SPECIAL PROGRAMS IN CUBA Mother - ChildMother - Child Blood CertificationBlood Certification Epidemiological SurveillanceEpidemiological Surveillance Placenta CertificationPlacenta Certification Minimum access neurosurgeryMinimum access neurosurgery

7. Severe Birth Defects HIV Hepatitis B Hepatitis C Congenital Hypothyroidism Phenilketonuria Biotinidase Def. (2002) Galactosemia (2002) Congenital Adrenal H. (2003) Others

8. CUBAN PRENATAL PROGRAMS RESULTS. Pregnants Screened: 2 524 163 Pregnants Screened: 2 524 163 Birth Defects Detected: 5 266 Birth Defects Detected: 5 266 Cuba 1986 – 2001 Only 1 mother to child HIV transmission since 1997 Only 1 mother to child HIV transmission since 1997 No mother to child HBV transmission in 95% No mother to child HBV transmission in 95% 2.08 x 1000

9. CONGENITAL HYPOTHYROIDISM CUBAN SCREENING PROGRAM. Newborns Screened: 2 108 288 Newborns Screened: 2 108 288 Hypothyroidism: 641 Hypothyroidism: 641 Permanent: 325 Permanent: 325 Transitory: 203 Transitory: 203 Under study: 113 Under study: 113 Incidence: 1 : 3295 Cuba 1986 – 9 -2001

10. BLOOD CERTIFICATION AND SEROLOGICAL SURVEILLANCE HIV1+2, HBsAg, HCV, DENGUE, CHAGAS 17,824,040 UMELISA 13,568,060 7,314,844

11. WHO HIV SCREENING ALGORITHM

12. VIH 1 and VIH 2 cases detected More than 20 million tested VIH 1 VIH 2 Year Seropositives DAVIH SUMA DETECTED 4072 LIVING WITH HIV/AIDS 3022