1. Advantages of a Syringe Driven Sample Introduction Accessory for ICP Spectrometry Jerry Dulude and Scott Bridger Glass Expansion

2. www.geicp.com Assist Automated Productivity Accessory

3. Glass Expansion www.geicp.com Assist components Niagara II Plus™ Rapid Rinse accessory Sample syringe plus drive Built in switching valve Built in peristaltic pump Optional internal standard syringe plus drive

4. Glass Expansion www.geicp.com Niagara II Plus

5. Glass Expansion www.geicp.com Niagara II Plus Flow Diagram

6. Glass Expansion www.geicp.com Niagara II Plus Flow Diagram-2

7. Glass Expansion www.geicp.com Screen display of Niagara II Plus software

8. Glass Expansion www.geicp.com ICP-MS Carryover Comparison Boron Moly Zinc Thallium

9. Glass Expansion www.geicp.com Niagara II Plus Selectable sample loop Optional internal standard lines Positive displacement pump Multi-stage valve Sample does not contact pump tubing

10. Glass Expansion www.geicp.com Standard operation Niagara II Plus Cycle timeRinse timeCycle timeRinse time Probe to sample 5055 Uptake delay 15055 Stabilization 100 0 Read 150 0 Probe to rinse 5000 Rinse 30 00 TOTAL 80303510 Time Saving for Niagara II Plus

11. Glass Expansion www.geicp.com Additional Assist Features Precision syringe and drive for sample Optional precision syringe and drive for internal standard

12. Glass Expansion www.geicp.com Syringe vs. peri pump

13. Glass Expansion www.geicp.com Advantages of Syringe Sample Delivery Computer control of delivery speed Broad selection of sample/IS ratio High precision for scanning systems

14. Glass Expansion www.geicp.com e.g. 20x dilution with peri pump @ 0.5ml/min uptake 0.38mm ID (orange/green) 1.75mm ID (blue/green) Pump speed=2rpm Very Noisy Signal

15. Glass Expansion www.geicp.com Assist Performance on a Elan9000 ICP-MS Uptake rate: 0.5ml/min Sample:.025ml/min IS:.475ml/min Dilution = 20x * Internal standards * *

16. Glass Expansion www.geicp.com Assist Productivity Enhancement Without AssistWith Assist Cycle timeRinse time Cycle timeSpray chamber rinse Probe/uptake line rinse Probe to sample 50550 Uptake delay150550 Stabilization100404 Read150 0 Probe to rinse50000 Rinse30 000 TOTAL8030291019

17. Glass Expansion www.geicp.com Productivity comparison* Standard operation Niagara II (w/o FIA) Niagara II Plus Assist 19% 27% 43% 52% * % of cycle devoted to measuring signal