1. Cancer survival in the UK and Republic of Ireland B Rachet 1, M Quinn 2, D Brewster 3, A Gavin 4, J Steward 5, H Comber 6, L Gonsalves 7, V Mak 8, MP Coleman 1 1 London School of Hygiene and Tropical Medicine 2 Office for National Statistics 3 Scottish Cancer Registry 4 Northern Ireland Cancer Registry 5 Welsh Cancer Intelligence Unit 6 Republic of Ireland Cancer Registry 7 West Midlands Cancer Intelligence Unit 8 Thames Cancer Registry CR UK funding

2. OBJECTIVE Estimate 1- and 5-year survival up to 2001 20 most common cancers England, Scotland, Wales, Northern Ireland, Republic of Ireland Cohort/complete and period approaches

3. MATERIAL All registered adult cancers Diagnostic period England, Scotland, Wales1991-99 Northern Ireland1993-99 Republic of Ireland1994-99 Follow-up: 31 December 2001

4. 190,998 1,531,819 40,365 69,309 106,170

5. RELATIVE SURVIVAL Maximum likelihood approach Sex, period of diagnosis (1991-95, 1996-99), country National life tables - centred on 1991 for 1991-95 deaths - centred on 1996 for 1996-2001 deaths Regional life tables for GOR analysis Unstandardised vs. age-standardised analyses Period analysis for short-term prediction

6. Breast cancer, women, UK and Republic of Ireland, 1991-99 Zero survival (%) Multiples (%) Included N. Ireland 1.50.95,866 R. of Ireland 1.71.09,590 Wales 6.01.516,475 Scotland 2.26.227,057 England 5.62.5250,299 309,287

7. BREAST Women diagnosed 1991-95

8. Breast, women diagnosed 1996-99 Breast, women diagnosed 1991-95

9. Colon cancer, men, UK and Republic of Ireland, 1991-99 Zero survival (%) Multiples (%) Included N. Ireland 4.32.51,964 R. of Ireland 4.72.93,336 Wales 12.72.04,675 Scotland 3.77.88,321 England 10.63.664,409 82,705

10. COLON Men diagnosed 1991-95

11. Colon, men diagnosed 1991-95 Colon, men diagnosed 1996-99

12. SUMMARY Preliminary results Discussion between cancer registries about potential differences in: registering and coding cancer records (non- malignant cases, zero survival, multiples, …) health care