Presentation is loading. Please wait.

Presentation is loading. Please wait.

中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Trends in the survival of patients with nasopharyngeal carcinoma 1976-2005 in Sihui city, Guangdong province,

Published byRodney Bridges Modified over 9 years ago

Similar presentations

Presentation on theme: "中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Trends in the survival of patients with nasopharyngeal carcinoma 1976-2005 in Sihui city, Guangdong province,"— Presentation transcript:

1 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Trends in the survival of patients with nasopharyngeal carcinoma 1976-2005 in Sihui city, Guangdong province, P.R. of China: a population-based study Q ing Liu, Jinou Chen, Qihong Huang, Yanhua Li Cancer Center, Sun Yat-sen University Sihui Cancer Institute

2 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER NPC Epidemiological Charateristics in Sihui Incidence rate of NPC: 30.9 in male and 13.0 in female Mortality rate of NPC: 22.0 in male and 7.7 in female Incidence rates and mortality rates of NPC kept stable Comparing to the reduction in HK, TW, LA in USA

3 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Trend of NPC incidence 1988-2002 in HK

4 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Trend of NPC incidence 1978-2002 in Sihui

5 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Materials and methods Cancer registry system since 1973 in Sihui Follow up system for NPC cases since 1978 1761 incidence cases of NPC were chose during 1976-2005 Follow up to the end of 2006, Max follow up year=30.4 1239 (70.3%) cases with pathological evidence

6 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Materials and methods Kaplan–Meier estimate for survival rates Cox proportional hazards regression for risk factor screening Risk factors: gender,age,period of diagnosis,clinical stage, pathological status,diagnosis medical unit were analyzed

7 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Materials and methods Relative survival probabilities for NPC were assessed by matched sex, age group, period of diagnosis with general population Age-specific death rates and life table of Sihui general population was available based on death registry system SURV3 was used for relative survival rate estimation SAS 9.2 for other statistical analyses

8 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Results

9 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Characteristics of patients with NPC 1976-2005 Gender N % Male118967.5 Female 57232.5 Age at diagnosis <40 49828.2 40- 54530.9 50- 41423.5 60+ 30417.3

10 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Characteristics of patients with NPC 1976-2005 Clinical stage N % I107 6.1 II54631.0 III46726.5 IV119 6.8 Unknown52229.6 Pathological diagnosis WHO I 159 9.0 WHO II/III108061.3 Unknown 52229.6

11 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Characteristics of patients with NPC 1976-2005 Period diagnosed N % 1976-40923.2 1986-47226.8 1993-53430.3 2000-34619.6 Diagnostic hospital CC107661.1 Other 68538.9

12 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Five year survival of NPC patients in Sihui MTS OS(95%CI) RS(95%CI) All cases5.150.5(48.1-52.9)60.3(57.5-63.1) Gender Male4.548.4(45.5-51.3)59.3(55.8-62.8) Female6.254.5(50.4-58.7)62.2(57.6-66.8) Age at diagnosis <408.756.4(51.9-60.9)59.4(54.7-64.1) 40-5.953.9(49.6-58.1)60.1(55.4-64.8) 50-4.848.7(43.8-53.6)62.5(56.3-68.6) 60+2.836.4(30.8-41.9)59.1(50.5-67.6)

13 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Five year survival of NPC patients in Sihui MTS OS(95%CI) RS(95%CI) Clinical Stages I14.473.7(65.3-82.1) 85.2(75.8-94.5) II6.357.4(53.1-61.7) 69.4(64.5-74.3) III2.838.3(33.8-42.8) 44.7(39.5-50.0) IV2.331.5(22.8-40.2) 37.9(27.6-48.2) Unknown6.152.8(48.4-57.2) 64.4(59.2-69.6) Path WHO I5.149.8(41.1-58.6)56.9(52.3-61.5) WHO II/III5.552.1(49.1-55.1)62.3(58.8-65.8) Unknown4.246.4(42.0-50.9)58.8(53.5-64.1)

14 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Five year survival of NPC patients in Sihui MTS OS(95%CI) RS(95%CI) Period diagnosed 1976-19853.842.5(37.8-47.3) 51.8(46.2-57.4) 1986-19924.043.4(39.0-47.9) 51.1(45.9-56.3) 1993-19995.552.1(47.8-56.3) 62.5(57.5-67.6) 2000-2005 -69.8(64.1-75.4) 84.8(79.1-90.6) Diagnostic Hospital CC5.552.3(49.3-55.3) 62.3(58.8-65.8) Others4.347.4(43.5-51.2) 56.9(52.3-61.5)

15 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Risk factors related to death from NPC by Multivariate Cox Regression HR 95%CI GenderMale1.00 Female0.760.65-0.90 Age<401.00 40-1.210.99-1.49 50-1.511.22-1.88 60+2.221.73-2.84 StageI1.00 II1.611.17-2.22 III2.611.89-3.60 IV3.412.34-4.99 HistoWHOII/III1.00 WHO I1.281.00-1.64 Period1976-19851.00 1986-19920.760.63-0.91 1993-19990.550.45-0.68 2000-20050.280.20-0.40

16 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Observed and relative survival (95%CI) of NPC in Sihui 1976-2005

17 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Relative survival of NPC, stage I and II

18 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Relative survival of NPC, stage III and IV

19 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Conclusion Significant improvement of NPC survival No change of proportion of stage of NPC cases Improved radiotherapy might contribute to survival of NPC Screening for NPC will definitely increase survival of NPC May predict a reduction of mortality rates of NPC in Sihui

20 中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER screening

Download ppt "中山大学肿瘤防治中心 SUN YAT-SEN UNIVERSITY CANCER CENTER Trends in the survival of patients with nasopharyngeal carcinoma 1976-2005 in Sihui city, Guangdong province,"

Similar presentations

1 肿瘤防治科 Dept. of Cancer Ctr. & Prevention Pattern of the Incidence of Thyroid Cancer before and after Universal Salt Iodization in Shanghai Ying ZhengMD,

1 肿瘤防治科 Dept. of Cancer Ctr. & Prevention Pattern of the Incidence of Thyroid Cancer before and after Universal Salt Iodization in Shanghai Ying ZhengMD,
Am J Gastroenterol 2012; 107:46–52. Drmohammad Sadrkabir.

Am J Gastroenterol 2012; 107:46–52. Drmohammad Sadrkabir.
HIV and STI Department - Centre for Infections Predictors of non-AIDS related death in a national cohort of HIV-diagnosed adults Meaghan Kall, Ruth Smith,

HIV and STI Department - Centre for Infections Predictors of non-AIDS related death in a national cohort of HIV-diagnosed adults Meaghan Kall, Ruth Smith,
Trends in incidence and mortality, England 1988 to 2008.

Trends in incidence and mortality, England 1988 to 2008.
Pier Luigi Filosso, MD University of Torino, Department of Thoracic Surgery The Impact of Adjuvant Chemotherapy in Pulmonary Large Cell Neuroendocrine.

Pier Luigi Filosso, MD University of Torino, Department of Thoracic Surgery The Impact of Adjuvant Chemotherapy in Pulmonary Large Cell Neuroendocrine.
Prognostic factors for breast cancer survival in affluent and deprived areas Jasmina Stefoski-Mikeljevic.

Prognostic factors for breast cancer survival in affluent and deprived areas Jasmina Stefoski-Mikeljevic.
© Cancer Research UK 2003 Registered charity number 1089464 Leukaemia The statistics in this presentation are based on the Leukaemia CancerStats report.

© Cancer Research UK 2003 Registered charity number Leukaemia The statistics in this presentation are based on the Leukaemia CancerStats report.
Assessment of Lupus (SLE) Mortality in a Patient-Based Community Data Bank Frederick Wolfe 1, Kaleb Michaud 1,2, Tracy Li 3, Robert S. Katz 4 1 National.

Assessment of Lupus (SLE) Mortality in a Patient-Based Community Data Bank Frederick Wolfe 1, Kaleb Michaud 1,2, Tracy Li 3, Robert S. Katz 4 1 National.
A 14-gene prognosis signature predicts metastasis risk in node-negative, estrogen receptor-positive, Tamoxifen-treated breast cancer in different ethnogeographic.

A 14-gene prognosis signature predicts metastasis risk in node-negative, estrogen receptor-positive, Tamoxifen-treated breast cancer in different ethnogeographic.
Essentials of survival analysis How to practice evidence based oncology European School of Oncology July 2004 Antwerp, Belgium Dr. Iztok Hozo Professor.

Essentials of survival analysis How to practice evidence based oncology European School of Oncology July 2004 Antwerp, Belgium Dr. Iztok Hozo Professor.
Suicide in Canada Numbers, Rates, and Methods. Index of Slides 1. Number of Suicides, Canada, 2000-2003 2. Number of Suicides by Age Group, Males, 2003.

Suicide in Canada Numbers, Rates, and Methods. Index of Slides 1. Number of Suicides, Canada, Number of Suicides by Age Group, Males, 2003.
Dr Laura Bonnett Department of Biostatistics. UNDERSTANDING SURVIVAL ANALYSIS.

Dr Laura Bonnett Department of Biostatistics. UNDERSTANDING SURVIVAL ANALYSIS.
Skull Base Chordoma and Chondrosarcoma: Changes in National Radiotherapy Patterns and Survival Outcomes Henry S. Park, MD, MPH; Kenneth B. Roberts, MD;

Skull Base Chordoma and Chondrosarcoma: Changes in National Radiotherapy Patterns and Survival Outcomes Henry S. Park, MD, MPH; Kenneth B. Roberts, MD;
INCIDENCE AND SURVIVAL TRENDS OF COLORECTAL CANCER FROM 2002 TO 2011 BE Ansa; E Alema-Mensah; MD Claridy; JQ Sheats; B Fontenot, and SA Smith Georgia Regents.

INCIDENCE AND SURVIVAL TRENDS OF COLORECTAL CANCER FROM 2002 TO 2011 BE Ansa; E Alema-Mensah; MD Claridy; JQ Sheats; B Fontenot, and SA Smith Georgia Regents.
Statistics about unknown primary tumors Riccardo Capocaccia National Centre for Epidemiology, Surveillance and Health Promotion Istituto Superiore di Sanità,

Statistics about unknown primary tumors Riccardo Capocaccia National Centre for Epidemiology, Surveillance and Health Promotion Istituto Superiore di Sanità,
Management and Development for Health (MDH)

Management and Development for Health (MDH)
Life expectancy of patients treated with ART in the UK: UK CHIC Study Margaret May University of Bristol, Department of Social Medicine, Bristol.

Life expectancy of patients treated with ART in the UK: UK CHIC Study Margaret May University of Bristol, Department of Social Medicine, Bristol.
© Cancer Research UK 2006 Registered charity number 1089464 The statistics in this presentation are based on the Bowel CancerStats report published in.

© Cancer Research UK 2006 Registered charity number The statistics in this presentation are based on the Bowel CancerStats report published in.
Breast cancer in elderly patients (70 years and older): The University of Tennessee Medical Center at Knoxville 10 year experience Curzon M, Curzon C,

Breast cancer in elderly patients (70 years and older): The University of Tennessee Medical Center at Knoxville 10 year experience Curzon M, Curzon C,
© Cancer Research UK 2011 Registered charity in England and Wales (1089464) and Scotland (SC041666) Colorectal Cancer - UK December 2011 For more information.

© Cancer Research UK 2011 Registered charity in England and Wales ( ) and Scotland (SC041666) Colorectal Cancer - UK December 2011 For more information.

Similar presentations

Ads by Google