1. NIH Activities Related to Big Data Jerry Sheehan Assistant Director for Policy Development National Library of Medicine Board on Research Data and Information - National Academies Washington, DC 23 September 2013

2. Context: Data and Informatics Working Group Report – June 2012  Biomedical research generating large volumes of data  Diverse data types (e.g., omics, imaging, phenotype, clinical)  Bottleneck is analysis to generate knowledge from data acd.od.nih.gov/diwg.htm 23 SEP 2013BRDI 2

3. Scientific Data Council (SDC) Big Data to Knowledge (BD2K) Associate Director for Data Science (ADDS) Elements of NIH Approach to Big Data 23 SEP 2013BRDI 3

4. 1.Facilitating Broad Use of Biomedical Big Data 2.Developing and Disseminating Analysis Methods and Software for Biomedical Big Data 3.Enhancing Training for Biomedical Big Data 4.Establishing Centers of Excellence for Biomedical Big Data BD2K: Programmatic Areas 23 SEP 2013BRDI 4

5. BD2K: Funding Plan  Initial 7-year funding plan: FY2014 – FY2020  Ramps to > $100M by FY2017  Funding model:  Early front-loading contributions by Common Fund  Increasing Institutes/Centers’ contributions  Complete budgetary ‘adoption’ by Institutes/Centers by FY2020 to ensure sustainability  FY13 – seed funding for information gathering 23 SEP 2013BRDI 5

6. Broad Use of Big Data: Data Catalog - Aug 21-22 Enabling Research Use of Clinical Data - Sept 11-12 Frameworks for Data Standards - Sept 25-26 Software: Software Catalog – Feb 2014 Underserved Areas – Date TBD Platforms for Data Analysis – Date TBD Training: Big Data and Training – July 13-14 Centers: Data Integration - Spring 2014 Workshops 23 SEP 2013BRDI 6

7. Requests for Information (RFIs) 23 SEP 2013BRDI 7

8. Funding Opportunity Announcement Investigator-Initiated Centers of Excellence 23 SEP 2013BRDI 8

9. For More Information: BD2K Website http://bd2k.nih.gov 23 SEP 2013BRDI 9

10. But there’s more...  NIH Genomic Data Sharing Policy  Promotes sharing, for research purposes, of large- scale human and nonhuman genomic data  Draft published on 20 September 2013 for public comment  Federal Register Notice http://www.federalregister.gov/a/2013-22941. http://www.federalregister.gov/a/2013-22941  Pdf version available at: https://s3.amazonaws.com/public- inspection.federalregister.gov/2013-22941.pdf. https://s3.amazonaws.com/public- inspection.federalregister.gov/2013-22941.pdf  Comments due by November 20.  More information at http://gds.nih.gov/http://gds.nih.gov/ 23 SEP 2013BRDI 10