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Published byMargaretMargaret Barber Modified over 9 years ago
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Light Microscopy Bright Field Fluorescence Phase-Contrast Differential Interference Contrast (DIC)
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Electron Microscopy (EM) Scanning EM Transmission EM
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Chemical Composition of Cells Pg. 58
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Pg. 79
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Chemical Bond Energies
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Gene Expression
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Monomer/Polymer
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Nitrogenous Bases of DNA and RNA Pg. 76
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Pg. 175
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3’ 5’
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0.34 nm Pg. 171 Major Groove Minor Groove
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Supercoiled DNA Non-supercoiled DNA (relaxed)
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Werner Syndrome 15 yrs. 48 yrs. Mutation in gene encoding RecQ helicase
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Pg. 175
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3’ 5’
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Human Karyotype Pg. 179
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RNA Molecules 5’ 3’
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Pg. 74
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(Pgs. 74-75) Amino Acid Side Chains
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Extra carbon atom!
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ß-Sheet alpha-helix
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Hydrophobic Interactions in Tertiary Structure
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Representations of Protein Tertiary Structure Backbone Ribbon Wire Frame Space Filling Pg. 132
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Quaternary Structure Pg. 141
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Chloride Ion Channel Protein
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Comparison of Protein Primary Structure Cyclin-dependent Kinase Proteins
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Gene Expression Pg. 230
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Pg. 202 RNA Synthesis OH
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Pg. 233
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1 µm Pg. 233
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Fig. 7-20
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Exon/Intron Organization of Eukaryotic Genes Pg. 238
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Sequence Structure of Introns
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Pg. 239
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Pg. 241 Alternative Splicing
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Pg. 237 5’ Guanine Cap Structure
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Cytosol Nucleus Mitochondria Secreted ER Golgi Endosome Lysosome Transmembrane
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Reading Frames in RNA
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tRNA Synthetase tRNA Amino Acid Synthetase (blue) Editing Domain
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“Editing” by tRNA Synthetase
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Large Subunit RNA Secondary Structure
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Small Ribosomal Subunit Pg. 253
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3’ mRNA Structure
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Pg. 253 Initiation of Translation
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Pg. 252
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tRNA Release Factor (RF)
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Co-translational Protein Folding
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Protein Folding by “Chaperones”
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Transcriptional Activator Transcriptional Repressor
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Pg. 257 Ubiquitin-dependent Protein Degradation Proteasome Amino acids + Ub Protein Ub-Ub-Ub Protein + Ub Ubiquitin Ligase
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Coding and catalysis Coding Coding intermediate
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Superficial Infections Systemic Infections Fungal Disease
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Onochomycosis
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AN2690 Structure
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Figure 1A
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Figure 1B
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Figure 3 AN2690
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