1. Direct and/or Microscopic examination Observation 1 Observation 2 Aerobic culture Observation 1 : positive Obs 2 : 1st microorganism : staph.aur Obs 3 : 2nd microorganism : bact.fr : the subject of this study (e.g. a sputum) Anaerobic culture Observation 1 : positive Observation 2 : 1st microorganism : staph.aur Findings on one isolate : « staph.aur » (the isolate) Which one is it? Antiobiogram Obs : concentration Antibiotic 1 Antibiotic 2 Microbio entry in XD-LAB: The issue

2. Direct and/or Microscopic examination Observation 1 Aerobic culture Obs 1 : positive Obs 2 : 1st microorganism : staph.aur : the subject of this study (e.g. a sputum) Anaerobic culture Obs 1 : positive Obs2 : microorganism = staph.aur Findings on isolate : « staph.aur » (the isolate) This is the one! Antiobiogram Obs : concentration Microbio entry in XD-LAB: Solution a) with <code code="----------" codeSystem="2.16.840.1.113883.6.96" codeSystemName="SNOMED-CT" displayName="Staph.aur"> <name code="-----" codeSystem="2.16.840.1.113883.6.96" displayName="culture"/> <value code="------" codeSystem="2.16.840.1.113883.6.96" displayName=" aerobic"/>

3. Direct and/or Microscopic examination Observation 1 Observation 2 Aerobic culture Observation 1 : positive Obs 2 : 1st microorganism : staph.aur Obs 3 : 2nd microorganism : bact.fr : the subject of this study (e.g. a sputum) Findings on one isolate : « staph.aur » (the isolate) Here’s the one ! Antiobiogram Obs : concentration Antibiotic 1 Antibiotic 2 Microbio entry in XD-LAB: The issueMicrobio entry in XD-LAB: Solution b) : structural change (CP) Anaerobic culture Observation 1 : positive Observation 2 : 1st microorganism : staph.aur Findings on one isolate