1. Ch. 11 Complex Heredity

2. 11.2 Complex Patterns of Inheritance These do not follow the same patterns discussed by Mendel Ex.

5. Incomplete dominance – the heterozygous phenotype is an intermediate phenotype between 2 homozygous phenotypes. Aka - blending Draw & show self-fertilization of F1

6. Codominance – both alleles are expressed in the heterozygous condition. Ex. Sickle cell disease

8. This person is heterozygous for sickle cell disease. Has both normal red blood cells & sickle cells Does not transport Oxygen as well If hetero - can still lead a normal life

9. Malaria - Malaria is caused by a parasite called Plasmodium, which is transmitted via the bites of infected mosquitoes. In the human body, the parasites multiply in the liver, and then infect red blood cells. Symptoms of malaria include fever, headache, and vomiting, and usually appear between 10 and 15 days after the mosquito bite. If not treated, malaria can quickly become life-threatening by disrupting the blood supply to vital organs. In many parts of the world, the parasites have developed resistance to a number of malaria medicines.

14. Shade next picture – p.303

16. Multiple alleles – some forms of inheritance are marked by more than 2 types of alleles Ex. Blood type

17. ABO blood groups have 3 forms of alleles (AB markers) IA, IB, I (on board) p304 Universal donor: O Universal acceptor:AB

18. Rh Factor: blood protein (+ has the protein) Either + or – + is dominant 85% of population

19. Blood type Percent of Americans with this type Who can receive this type O+ 37%B+ 10% O– 6B- 2% A+ 34AB+ 2% A– 6 AB– 1

20. Cross a parent with heterozygous A with AB (2 factor cross)

21. Sex chromosomes Humans have 23 pair of chromosomes 22 are called autosomes 1 pair are the sex chromosomes

22. XX = female XY = male Draw punnet square p. 305

25. Sex – linked traits Traits controlled by genes located on the X chromosome are called sex-linked traits

26. Ex. Color blindness P307 draw punnet square