2. By: Garrett Allison & Siddhi

3.  Sickled cells tend to clog arteries and cause serious cardiovascular problems.

4.  SCD affects the digestive system quite a bit with the medications needed. Radiation causes vomiting and many other problems.

5.  SCD affects the immune system by causing the patients who have it to be more susceptible to infections.  These infections could be life threatening and cause other systems to start to shut down.  Without the immune system working properly the body could be threatened 24/7.

6. o Small strokes over time Not immediately noticeable Worsening mental functions o Strokes caused by vessel blockage o Strokes caused by aneurysms o Aneurysms are common, not able to treat surgically

7. o Infection from viruses (chlamydia or mycoplasma) o Blood vessel blockage Blood clots Fat embolisms o Asthma o Over time: Susceptibility to infections Lung damage leads to damage in airways

8.  SCD affects the urinary system because the body is more susceptible to infections it can cause a UTI (Urinary Tract Infection).  Another problem that can occur is Hematuria. Which is blood in the urine.  A urinary tract infection if goes untreated can be deadly.  SCD causes hematuria because; RBCs form an abnormal crescent shape, resulting in less oxygen delivered to the body’s tissues, clogging of small blood vessels, and disruption of healthy blood flow