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© 2006 Thomson-Wadsworth Protein: Amino Acids
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© 2006 Thomson-Wadsworth Amino Acids
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© 2006 Thomson-Wadsworth Amino Acids Nonessential amino acids –a.k.a dispensable amino acids Essential amino acids –a.k.a indispensable amino acids Conditionally essential amino acids
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© 2006 Thomson-Wadsworth
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An Essential Amino Acid
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© 2006 Thomson-Wadsworth Nonessential Amino Acids
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© 2006 Thomson-Wadsworth Proteins Peptide bond
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© 2006 Thomson-Wadsworth Proteins Dipeptide
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© 2006 Thomson-Wadsworth Proteins Tripeptide
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© 2006 Thomson-Wadsworth Proteins Polypeptide
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© 2006 Thomson-Wadsworth Proteins Amino acid sequences
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© 2006 Thomson-Wadsworth Protein shape and function
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© 2006 Thomson-Wadsworth Proteins Protein denaturation
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© 2006 Thomson-Wadsworth Protein Digestion Stomach –HCl –Pepsinogen pepsin Proenzyme
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© 2006 Thomson-Wadsworth Protein Digestion Small intestine –Proteases Intestinal and pancreatic –Peptidases
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© 2006 Thomson-Wadsworth
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Protein Absorption Carriers Capillaries Absorption misconceptions –Enzyme/amino acid supplements
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© 2006 Thomson-Wadsworth Protein Synthesis Delivering the instructions –DNA mRNA
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© 2006 Thomson-Wadsworth Protein Synthesis
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© 2006 Thomson-Wadsworth Protein Synthesis
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© 2006 Thomson-Wadsworth Protein Synthesis
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© 2006 Thomson-Wadsworth Protein Synthesis Sequencing errors
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© 2006 Thomson-Wadsworth
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Protein Synthesis Nutrients and gene expression
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© 2006 Thomson-Wadsworth Roles of Proteins Building material –Growth –Maintenance
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© 2006 Thomson-Wadsworth Roles of Proteins Enzymes
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© 2006 Thomson-Wadsworth Roles of Proteins Hormones
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© 2006 Thomson-Wadsworth Roles of Proteins Regulation of fluid balance –Edema Acid-base regulation –Acidosis –Alkalosis
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© 2006 Thomson-Wadsworth Transport proteins
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© 2006 Thomson-Wadsworth Roles of Proteins Immunity –Antibodies –Antigens
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© 2006 Thomson-Wadsworth Roles of Proteins Source of energy Other roles
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© 2006 Thomson-Wadsworth Protein Metabolism Protein turnover –Amino acid pool Nitrogen balance –Positive nitrogen balance –Negative nitrogen balance
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© 2006 Thomson-Wadsworth Protein Metabolism Using amino acids to make proteins Using amino acids to make nonessential amino acids
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© 2006 Thomson-Wadsworth Protein Metabolism Using amino acids to make other compounds –Neurotransmitters Using amino acids for energy and glucose
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© 2006 Thomson-Wadsworth Protein Metabolism Deamination Using amino acids to make fat
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© 2006 Thomson-Wadsworth Protein Quality High-quality proteins Digestibility –Animal vs. plant Amino acid composition –Limiting amino acid
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© 2006 Thomson-Wadsworth Protein Quality Reference protein Complementary proteins
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© 2006 Thomson-Wadsworth Protein Quality PDCAAS –Protein digestibility- corrected amino acid score
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© 2006 Thomson-Wadsworth Food Labels Quantity of protein Daily Value –50 g protein 10% of a 2000 kcal diet
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© 2006 Thomson-Wadsworth Protein-Energy Malnutrition (PEM) Acute PEM Chronic PEM
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© 2006 Thomson-Wadsworth Protein-Energy Malnutrition (PEM) Marasmus Kwashiorkor Marasmus-kwashiorkor mix
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© 2006 Thomson-Wadsworth
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Protein-Energy Malnutrition (PEM) Infections –Dysentery Rehabilitation
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© 2006 Thomson-Wadsworth Health Effects Heart disease Cancer Adult bone loss –osteoporosis
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© 2006 Thomson-Wadsworth Health Effects Weight control Kidney disease
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© 2006 Thomson-Wadsworth Recommended Intakes RDA –0.8 g/kg/day –10% - 35% of energy intake
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© 2006 Thomson-Wadsworth Recommended Intakes Adequate intake Protein in abundance
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© 2006 Thomson-Wadsworth Supplements Protein supplements Amino acid supplements
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© 2006 Thomson-Wadsworth Vegetarian Diets
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© 2006 Thomson-Wadsworth Vegetarian Diets Health benefits
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© 2006 Thomson-Wadsworth Vegetarian Diets Diet planning –Protein Lacto-ovo-vegetarians Meat replacements –Texturized vegetable protein
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© 2006 Thomson-Wadsworth Vegetarian Diets Vitamins and minerals –Lactovegetarians –Vegans
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© 2006 Thomson-Wadsworth Vegetarian Diets Omega-3 fatty acids
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© 2006 Thomson-Wadsworth Vegetarian Diets Vegetarian diets through the life span –Pregnancy and lactation –Infancy –Childhood and adolescence
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© 2006 Thomson-Wadsworth Vegetarian Diets Healthy food choices –Macrobiotic diets
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