1. Confidential Hovione © 2014 1 Highlighting projects for Erlangen: Synergies Finder Route 1 – Pro-Active Approach -Identify intra-Innostar competencies -Identify key projects & link to the different CLC partners with the relevant competencies -Fill-in the white spots (gaps) by addressing the needs to the other CLCs and request collaboration for specific projects

2. / 19InnoSTARS24/02/20152 Intra-CLC Competencies Matrix (for information: will be derived from Patricia’s contacts table)

3. / 19InnoSTARS24/02/20153 Partner Competencies Industry Competences Academic Competences Healthcare Competences Omics techno- logies Big data, Bioinform atics Epidemio- logy Public health Biobanks Bio- imaging Innovation pipeline Health care management Patient cohorts Patient treatment protocols Clinical study protocols Health data management Patient cohorts National/ International networks University Spin-offs Core facilities – fee-for- service Semmelweis University competencies for the knoweldge triangle

4. / 19InnoSTARS24/02/20154 Project - Innostars platform for enabling targeted anticancer therapy Finding Intra-CLC Competencies Semmelweis University Yyy yyy Semmelweis University GYEMSZI Xxx XXX New biomarkers Clinical Trials Biobanks Imaging technology GE XXX Big Data, bioinformati cs Omics techno- logies Health care management Patient follow up Imaging Patient cohorts, stratification Networks, regirstries, Joint Action DEVELOPMENT OF AN ANTICANCER THERAPY PLATFORM Personalized medicine Omics technologies Biomarkers

5. / 19InnoSTARS24/02/20155 Building collaborations along the value-chain Strongest druggable target Internet-based analytical platform Database of NGS data Personal kinome discovery software Strongest druggable target Internet-based analytical platform Database of NGS data Personal kinome discovery software Omics, imaging, Data mining Omics, imaging, Data mining Patients, Health care providers, Health insurance companies GE Innostars Imdustries Semmelweis University Innostars Universities Pharma companies Innostars Healthcare providers GYEMSZI Project name: Innostars platform for enabling targeted anticancer therapy New targets New targets Clinical validation Clinical validation Inter-disciplinary Platform Inter-disciplinary Platform Pharma companies Innostars Universities Innostars Health- care providers

6. / 19InnoSTARS24/02/20156 Healthy Brain – Multidisciplinary approach for healthy ageing using imaging, omics and IT tools Finding Intra-CLC Competencies DEVELOPMENT OF A PLATFORM Semmelweis University Universidade de Coimbra Yyy yyy Semmelweis University GYEMSZI Xxx mHealth tools ehealth New biomarkers Clinical Trials Biobanks Imaging technology GE Abiomics Big Data, bioinformati cs Omics techno- logies Health care management Patient follow up Imaging Patient cohorts, stratification Networks, regirstries, Joint Action

7. / 19InnoSTARS24/02/20157 Semmelweis University (SU) - GE – High-maturity project Healthy Brain – Multidisciplinary approach for healthy ageing using imaging, omics and IT tools Patients selection, biobanking, database building Patients selection, biobanking, database building Imaging (PET-CT/MRI) biomarkers Imaging (PET-CT/MRI) biomarkers Data mining Patient use Patient use SU GE Coimbra Univ SU GE Abiomics GE SU Research Products PI’s Molnar MJ Katona V Contact InnoSTARS Lilla.farkas@semmelweis- univ.hu mHealth application mHealth application Genomic biomarkers Genomic biomarkers Patient follow up, validation GE SU GYEMSZI SMEs SU GYEMSZI Health economic use Health economic use