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Published byDennis Bryan Modified over 9 years ago
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By Michael Riel
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Joints: Physical Connection between 2 or more bones to cause mobility. Example: the jaw and the mandible, phalanges to metacarpals etc. Cause mobility TMJ- pain, inflammation and stiffness in the joint between the mandible and jaw bone (Temporary-Permanent). How? With the presence of Metalloproteinase, which are labeled MMP-7 and MMP-9 for short (Loredo).
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Condylotomy surgical procedure where the condyle of the bone is separated from the joint for “remodeling”the bone structure. 70%-90% success on TMJ mobility (Puricelli) What about arthritis? To be more specific, osteoarthritis (location: hinje joint for the hand)?
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4 groups: Control, TMJ, Control, Arthritis Voluntary Patients with a medical history of TMJ or arthritis (confidential). Medical examinations are required for the experiments. Begin experiment with Anesthesia($100,000/L) Proceed with condylotomy and the use of adrenocortical steroids ($150,000/lb).
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Use surgical condylotomy procedure on 4 groups: Incision in the mouth for TMJ and control TMJ. Incision on the skin for arthritis and control. Separate the bone from the joint. Use Steroid to be placed around the joint for repression and relaxant to cause less inflammation and provide restructure of the joint. Rehabilitation Observe and record 4 times a day (6 hours) for 8-12 weeks.
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Success: No pain for all groups. Growth and restructure of tissues in the cartilage. Same mobility in control groups. More mobility in TMJ and arthritis. Failure: Stiffness starts developing in the joint in control groups. Same symptoms arises from arthritis and TMJ.
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If we are able to create more mobility for patients with TMJ and osteoarthritis, we can use this factor as a start of reversing and relieve the symptoms of arthritis. More resources and data for future experiments.
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http://www.cdc.gov/arthritis/data_statistics/national_nhis.htm http://www.statcan.gc.ca/pub/82-625-x/2012001/article/11657- eng.htm http://www.cdph.ca.gov/programs/capp/Documents/The%20F ive%20Most%20Common%20Forms%20of%20Arthritis.pdf Puricelli Edella, Adriana Corsetti, Julieta Tavares, Giuliano Luchi. "Clinical-surgical treatment of temporomandibular joint disorder in a psoriatic arthritis patient." (2013) 9:11; 1-7. Loredo, Cortez, Ramon Leonardi, Geo Musumeci,, and. "An ex vivo study on immunohistochemical localization of MMP-7 and MMP-9 in temporomandibular joint discs with internal derangement." (2013): 57:e12 75-59. Print.
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