1. Section 3.0 DNA is the Inherited Material Responsible for Variation

2. Goals for this Section: 1.Describe the relationship among chromosomes, genes, and DNA 2.Explain how DNA stores genetic information 3.Distinguish between cell division during sexual and asexual cell reproduction 4.Investigate the transmission of characteristics from parents to offspring

3. Goals – Continued… 5.Identify examples of different types of inheritance 6.Identify examples of dominant and recessive characteristics

4. 3.1 – DNA – The Transmitter of Genetic Code Variation within a species is necessary for the survival of the species The source of this variation is the genetic material that is present in all cells

5. DNA and Variation As you have seen, sexual reproduction involves recombining the genes of two parents in one offspring However, variation also exists in those species that reproduce asexually This is because of slight changes, or mutations in their DNA

6. What Produces Variation? Essentially, all variation results from slight differences in the genetic code of each individual This genetic code is contained in the molecule known as DNA Canadian scientist Oswald Avery was one of the first people to suggest that DNA was a molecule that stored information that coded for inherited characteristics

7. DNA DNA is an abbreviation for deoxyribonucleic acid All living organisms carry DNA in their cells In some cases, the DNA is found in the nucleus, but it also may be found elsewhere in the cell

8. DNA was first identified in 1869, but its role was not understood until 1944, when Avery confirmed its role in passing on heritable traits However, at this time, the actual structure of DNA was not understood

9. Watson & Crick In 1953, James Watson and Francis Crick determined that DNA has a structure similar to a spiral staircase http://www.chem.ucsb.edu

10. The Structure of DNA DNA consists of a sugar-phosphate backbone with nitrogen base pairs in-between http://www.biologycorner.com

11. The Genetic Code The instructions for the characteristics that an organism displays are contained in the genetic code The genetic code consists of the four nitrogen base pairs The sequence of these nitrogen bases makes up genes that code for proteins made by the cell

12. Chromosomes A chromosome is a single strand of DNA A single chromosome can hold numerous genes Human cells contain 46 chromosomes, arranged into 23 pairs However, other species have different numbers of chromosomes

13. Genes All genes come in pairs Each pair of genes carries DNA for the same trait (for example, leg length in a fly) These pairs of genes are always found at the same position on a chromosome However, the code for each gene in the pair may be different

14. Alleles Offspring will inherit genes from both of their parents http://www.csulb.edu

15. Multiple Genes & Alleles Often a trait depends not only on a single gene As well, there is often more than one or two possible alleles for a single trait

16. 3.2 – Cell Division Cell division can be associated with sexual or asexual reproduction The type of cellular division involved will affect the number of chromosomes present at the end of the process of cellular division

17. Mitosis Mitosis is the form of cellular division used during asexual reproduction http://www.bbc.co.uk

18. Meiosis Meiosis produces gametes (sex cells) http://www.bbc.co.uk

19. A Comparison of Mitosis and Meiosis CharacteristicMitosisMeiosis Original number of chromosomes per cell Final number of chromosomes per cell Number of cell divisions

20. 3.3 – Patterns of Inheritance For centuries humans have been breeding animals to enhance desired traits Over time, purebred strains of various types of animals and crops were developed

21. Genetics Terms Purebred Hybrid

22. More Genetics Terms Dominant Trait Recessive Trait

23. Example – Crossing Purebred White & Black Cats Assume the black coat colour is dominant to white in cats What would be the result of breeding a purebred white cat and a purebred black cat?

24. Example – Breeding of Hybrids Now assume that two of the offspring from the previous example are bred together What would be the results of this breeding?

25. Other Patterns of Inheritance Occasionally, some traits show incomplete dominance, where a trait is a mixture of the traits of the parents For instance, if a white snapdragon is crossed with a red snapdragon, the offspring will be pink

26. In some cases, because multiple alleles may be present, an offspring may not have traits similar to either parent Many traits are in fact far too complex to explain using simple patterns of dominant and recessive genes

27. Environmental Factors Although genes for a particular trait may be present, it may not be expressed because of environmental factors To be expressed, genes must be turned “on” or “off”, and this often depends on factors in the environment

28. Examples of Traits with Environmental Factors