1. Course title : Hematology (1)
Course code :MLHE-201
Supervisor : Prof Dr. Magda Sultan
14/11/2013.
Outcome :
The student will know :
-The definition of anemia .
-The classification of anemias .
-The diagnosis of anemias

2. Introduction To Anaemias
2013

3. Definition of anaemia Reduction below normal in the concentration of Hb or RBCs ( according to age and sex )

4. Adult male: Hb 13. 5-17. 5 g/dl RBCs 4. 5 – 6. 00 Adult female : Hb 12
Adult male: Hb g/dl RBCs 4.5 – 6.00 Adult female : Hb g/dl RBCs

5. The approach to the diagnosis : 1-Detection of the anaemia ( by accurate measurements of the patient values) 2-Type of the anaemia . 3-Investigations of the cause of anaemia

6. Laboratory evaluation of anaemia :
1-Study of the blood :
-Complete blood count ( Hb, Ht, RBCs, Red cell indices , WBC and platelets )
-Examination of stained blood film .
-Reticulocyte count .

7. 2- Other laboratory tests : -Serum iron ,TIBC, serum ferritin , B12, folate, Coomb's test , osmotic fragility , G6PD ,Hb electophoresis ,ESR , liver and kidney functions tests , thyroid tests ,bone marrow examination.

8. Classification of anaemias Morphologic classification :
Blood film + Red cell indices

9. 1-Microcytic Hypochromic anaemia :
MCV reduced and MCH reduced
2-Normocytic Normochromic anaemia :
MCV normal and MCH normal
3-Macrocytic anaemia :
MCV increased

10. Microcytic Hypochromic anaemia
Causes :
1-Iron deficiency anaemia .
2-Thalathemias.
3-Haemoglobinopathies.
4-Chronic disorders .

11. Investigations :
1-Serum iron .
2-TIBC .
3-Serum ferritin .
4-Haemoglobin electrophoresis .

12. Nomocytic Normochromic anaemia
Causes :
1-Haemolytic anaemia .
2-Post haemorrhagic anaemia .
3-Liver disease .
4- Renal disease .
5-Endocrine disorders .
6-Hypoplastic anaemia .
7-Bone marrow infiltration .

13. Investigations :
1-Reticulocyte count Coomb's test .
3-Hb electrophoresis Osmotic fragility .
5-G6PD Endocrine tests
7-Liver and renal function tests.
8-Bone marrow aspiration and biopsy

14. Macrocytic anaemia
Types :
1-Megaloblastic Non Megaloblastic
Causes :
1-Vitamin B12 deficiency Folate deficiency .
3-Haemolytic anaemia Haemorrhage .
5-Alcohol Liver and thyroid diseases.
7-Hypoplastic bone marrow.

15. Investigations :
1-Serum B Folate assay
3-Bone marrow examination
4-Reticulocyte count
5-Tests for liver and thyroid disorders .

16. Assignement :
Student name :
Title : Microcytic hypochromic anaemia .
Title:Normocytic normochromic anaemia

17. زينب عبد المنعم ابراهيم
Assignment
Student Name
Topic
محمد ابراهيم ابراهيم
محمد احمد فتوح
محمد احمد محمد
محمد انور عبد الغني
محمد خالد اسماعيل
محمد صالح السيد
محمد صلاح الدين جامع
محمد عادل خضر ابراهيم
Microcytic hypochromic anaemia
محمد علي رمضان النقيب
محمد هشام محمد فوده
محمد حمدي حسن
هبه الله محمد محمود
زينب عبد المنعم ابراهيم
احمد لطفي
ندي محمود احمد
محمود احمد سعد سعد عامر
Normocytic normochromic anaemia

18. Training Questions :
-Define anaemia .
-Mention the morphologic classifications of anaemias.
Reference book :
-Essential haematology -Dacie