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Published byAllan Sherman Modified over 9 years ago
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Prepared by: Dr. Mohamed Al-Shekhani. Kurdistan Board GEH Journal club.
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MOST OFTEN MISUNDERSTOOD BY GASTROENTEROLOGISTS. MAY OCCUR WITH OR WITHOUT DIGESTIVE VASCULAR OCCLUSION. WHATEVER THE MECHANISMS THE INCIDENCE IS INCREASING THE PROGNOSIS COULD BE IMPROVED BY AN INNOVATIVE MULTIMODAL & MULTIDISCIPLINARY MANAGEMENT INITIATED AT EARLY PRESENTATION.
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DIAGNOSIS MUST BE SUSPECTED WITH ANY SUDDEN, CONTINUOUS & UNUSUAL ABDOMINAL PAIN, CONTRASTING WITH NORMAL PHYSICAL EXAM INITIALY. THROMBO-ATHERO-EMBOLIC RISK FACTORS ARE OFTEN UNKNOWN AT PRESENTATION & NO BIOCHEMICAL TEST IS SPECIFIC. ABSENCE OF INDIVIDUAL RISK FACTORS OR NORMAL BIOLOGY MIGHT NOT DENY OR DELAY THE DIAGNOSIS, WHICH SHOULD BE CONFIRMED BY ABDOMINAL CT ANGIOGRAPHY IDENTIFYING GASTRO-INTESTINAL ISCHAEMIC INJURY, WITH OR WITHOUT VASCULAR OCCLUSION.
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GASTROENTEROLOGISTS HAVE A MAJOR ROLE IN THE MANAGEMENT, TO AVOID DEATH & LARGE INTESTINAL RESECTIONS, BY INITIATING & COORDINATING A MULTIDISCIPLINARY A/MULTIMODAL MANAGEMENT INCORPORATING A MEDICAL PROTOCOL, REVASCULARIZATION OF VIABLE DIGESTIVE SEGMENTS&RESECTION OF NON- VIABLE INTESTINE. THERAPEUTIC STRATEGY DEPENDS ON THE PRESENCE OF AT LEAST ONE OF THREE CRITERIA (NECROSIS, ORGAN FAILURE, OR ELEVATED SERUM LACTATE).
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IN THE EARLY STAGES, PATIENTS WITHOUT SURGICAL COMPLICATION, ORGAN FAILURE OR HIGH LACTATE LEVELS SHOULD BE TREATED MEDICALLY WITH ENDOVASCULAR REVASCULARIZATION WHENEVER POSSIBLE.
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AT LATER STAGES, SURGICAL MANAGEMENT REQUIRES BOTH RESECTION & REVASCULARIZATION. ANY FACTOR THAT MAY HAVE CONTRIBUTED TO THIS ISCHAEMIC STROKE (I.E ATHEROSCLEROSIS, CARDIAC EMBOLISM OR THROMBOPHILIA) SHOULD BE INVESTIGATED &TREATED, WITH PARTICULAR REFERENCE TO ISCHAEMIC COLITIS & NON-OCCLUSIVE MESENTERIC ISCHEMIA.
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