1. VERIS ™ by Electro-Diagnostic Imaging, Inc
VERIS ™ by Electro-Diagnostic Imaging, Inc. Redwood City, California, USA
Complete integrated System for Visual Electrophysiology
First in Multifocal Electrophysiology

2. Comprehensive Visual Electrodiagnostic Testing
Traditional (ISCEV Standard) Testing
EOG, Full-Field ERG & Flash VEP, Pattern ERG & VEP
Multifocal Testing
mfERG, mfVEP
Automated Ring Ratio Analysis
Optic Nervehead Component (Global Flash Paradigm)
...and more
M-Sequence Full-Field ERG, Pattern VEP, Pattern ERG
Full Kernel Analysis ./ Synthesis capability
User-Defined Custom Recording and Analysis Protocols
Customizable Reports

3. Apple OS X Platform Exceptionally stable
VERIS data can be stored automatically to any local, network, or Internet-accessible storage device
Choice of open or password-protected file locking of data, analysis settings, and recording settings files
Easy creation of pdf copies of reports for electronic medical records or communications without additional (3rd party) software
Easy to learn and fun to use!

4. VERIS Platform FG1 FMS IV Mac Pro Available Stimulators: FMS IV
EMS IV (not shown)
Fresnel Ganzfeld 1 (FG1)
Flat panel displays
Ganzfeld II (not shown)
Mac Pro
Grass
Amplifier

5. VERIS ™ 6 Software Four Levels Traditional CLINIC SCIENCE PRO
Traditional ISCEV protocols only
CLINIC
All Pre-programmed tests
Creating and editing reports
SCIENCE
All Pre-programmed tests,
Creation of new stimulation modes
Creation of new analysis schemes
PRO
All functions of SCIENCE
Advanced kernel synthesis and modeling ability

6. Real-time Internet support
from EDI
Available to all VERIS users by appointment
Real-time monitoring and control of your VERIS system from our California office for training and troubleshooting at your location
Fully encrypted with security controls to ensure privacy of medical information
Requires Internet connection

7. The Ganzfeld Stimulator
The Conventional Flash ERG Response
Response of the retina to a full-field flash derived by means of an electrode placed on or near the cornea of the eye.
The basic stimulator used for the derivation of this response is
The Ganzfeld Stimulator

8. ISCEV Standard
Ganzfeld Protocols

9. Flash ERG
Flicker ERG
Flash VEP
EOG
The EDI Ganzfeld 2
Full-Size Ganzfeld Stimulator

10. The Fresnel Ganzfeld FG1
Supports all Ganzfeld functions

11. FG 1 in handheld use
FG 1 is the only handheld Ganzfeld stimulator for binocular recording

12. The retina is not homogeneous in its anatomy and physiology.
The distribution of dysfunction is often characteristic for the disease and helpful for diagnosis and disease management.
Response Mapping with Multifocal Electrophysiology

13. mfERG mfVEP Hexagon array Monitor screen
120 scaled sectors stimulated with contrast reversing check patterns ~ 40
Corneal Electrode
Amplifier
Typical electrode
placement
Minimum 2 channels:
1 midline
1 lateral
Computer
Trace array
Inion
Right eye red
Left eye blue
120 focal VEPs
Response
density
Inter-ocular differences

14. Fundus Monitoring Stimulator FMS IV
Permits monitoring the patient’s fixation during stimulation
Single know spherical refraction with range > 20 diopteer
For
PERG
PVEP
mfERG
mfVEP
Stimulator unit includes:
High resolution color display
Eye camera for patient alignment
IR fundus camera for fixation monitoring

15. Eye Monitoring Stimulator EMS IV
Permits monitoring the patient’s eye during stimulation
Single know spherical refraction with range > 20 diopters
Stimulator unit includes:
High resolution color display
Eye camera for patient alignment
For
PERG
PVEP
mfERG
mfVEP

16. Clinical recording of multifocal ERGs takes 2 to 7 minutes per eye.
The time depends on
The spatial resolution (Veris offers up to 509 stimulus areas within the central 45 deg)
The electrode technique

17. Example from the Clinic:
Hydroxychloroquine Toxicity

18. Hydroxychloroquine Retinopathy
A small percentage of patients who take this drug for autoimmune disease develop a bullseye retinopathy.
This retinopathy is, at best, only partially reversible when the patient is taken off the drug.
For disease prevention, the mfERG is now often used for patient screening.

19. Relative sparing of center
Para-central depression
Relative sparing of center

21. P1 implicit times are within normal range!

22. Plot is automatically generated
red area between outside 30
Divided by total red area
Ring aveerages

23. The Multifocal VEP (mfVEP)
Placing recording electrodes on the scalp over the visual cortex
A sensitive test in unilateral and asymmetric diseases

24. Traces from the two eyes match well!
Normal mfVEP
Red traces : right eye
Blue traces : left eye
200 nV
200 ms
Traces from the two eyes match well!

25. Example from the Clinic:
Optic Neuritis

26. Optic Neuritis on right eye
acute phase
Record Dated:
Red traces : right eye
Blue traces : left eye
Right eye amplitudes severely depressed in central area.

27. Right eye amplitudes recovered but delayed in central area.
Record Dated:
Red traces : right eye
Blue traces : left eye
Optic Neuritis
Recovery 1
Right eye amplitudes recovered but delayed in central area.

28. Recovery of delays suggests re-myelination of fibers.
Record Dated:
Optic Neuritis
Recovery 2
Red traces : right eye
Blue traces : left eye
Recovery of delays suggests re-myelination of fibers.