2. Renal Tumor A-Primary renal tumors: 1- Parenchymal Tumors: -Benign Adenomas,Angiomyolipomas, Oncocytoma…,, -Malignant : Nephroblastoma(Wilms' Tumor). Adenocarcinoma. 0.

3. Renal Tumor 2-Urethelial tumors: Transitional cell cancer of renal pelvis&ueter. B- Secondary Tumors: 1ry sites in lung,breast,lymphomas.

4. Renal Tumors Wilm‘s Tumor : - common solid renal tumor of childhood. -Age : 3 yrs. -sex : 1:1. -5% bilateral. -Familial and non Familial -associated with congenital genitourinary abnormalities.

5. Renal Tumors Clinical presentation : Symptoms&Signs -Asymptomatic mass discovered by family member or physician during routine physical examination. -Abdominal pain,distention,anorexia,nausea, vomiting,fever,hematuria,hypertension.

9. Renal Tumors Laboratory: -Urinalysis. - Anemia. - Abnormal Liver function tests. X-RAY: -U.S. -I.V.P. -Chest-x-ray. -C.T.Abdomen. Needle biopsy:

10. Wilm‘s Tumors Pathology: Favorable : Unfavorable: Treatment: -Chemotherapy: in all stages. -Radiotherapy: in all stages except stage 1. & stage II F.H..

11. Adenocarcinoma of the kidney Called also Hypernephrom,Renal cell carcinoma. most common renal tumor in adult. Age:5 th -6 th decade. sex: male:female 2:1. Cell of origin:Proximal convoluted tubules. Etiology: -Cigarette smoking. (well documented) -shoes worker.,leather tanners,cadmium. -Hereditary,sporadic. -Acquired cystic disease in renal failure patients.

12. Adenocarcinoma of the kidney Pathology: -Grossly:yellow to orange. -Histologically,RCC mixed adenocarcinoma contain clear cells,granular cells,and sarcomatoid appearing cells. Metastasis: Direct invasion into renal vein,perinephric fat, and adjacent viscera. Distant Metastasis to lung, liver,bone,LNS.

13. Robson Staging: