1. EXTRACTING ARTERIAL BLOOD CURVE FROM PET IMAGE Images containing abdominal aorta

2. why  missing blood data  noninvasive alternative high costs of arterial sampling other problems with arterial sampling more reliable than arterialised venous sampling

3. method - what are we fitting  only once diameter of the vessel (needs initial value)  for all frames separately center of the vessel activity inside vessel activity of the surrounding area

4. how Known: C I =activity in PET image Unknown: C B =final input TAC C BG =background activity C A =activity inside arteria C I =(C A -C BG )*K+C BG => K distance from the centre of vessel

5. Adipose tissue study

6. problems & ideas  results are very dependent on diameter value  2D convolution might be used for testing

7. References Germano et al.: Use of Abdominal Aorta for Arterial Input Function Determination in Hepatic and Renal PET Studies: J Nucl Med 1992; 33:613-620