1. Fulminant Clostridium Difficile Colitis After Surgical Treatment of Cervical Destructive Spondyloarthropathy
by Tetsuro Ohba, Shigeto Ebata, Takashi Ando, Jiro Ichikawa, Devin Clinton, Tetsuo Kondo, and Hirotaka Haro
JBJS Case Connect
Volume 1(1):e2
July 27, 2011
©2011 by The Journal of Bone and Joint Surgery, Inc.

2. Lateral flexion (A) and extension (B) cervical spine radiographs demonstrated cervical spondyloarthropathy associated with hemodialysis.
Lateral flexion (A) and extension (B) cervical spine radiographs demonstrated cervical spondyloarthropathy associated with hemodialysis. T2-weighted sagittal MRI (C) shows spinal cord compression at multiple levels.
Tetsuro Ohba et al. JBJS Case Connect 2011;1:e2
©2011 by The Journal of Bone and Joint Surgery, Inc.

3. A CT scan of the abdomen and pelvis demonstrated mucous-membrane thickening (arrow) and edema of the entire colon.
A CT scan of the abdomen and pelvis demonstrated mucous-membrane thickening (arrow) and edema of the entire colon.
Tetsuro Ohba et al. JBJS Case Connect 2011;1:e2
©2011 by The Journal of Bone and Joint Surgery, Inc.

4. Autopsy specimen of the entire colon (A) and close-up view (B) revealed widespread pseudomembranes in the colon (arrow).
Autopsy specimen of the entire colon (A) and close-up view (B) revealed widespread pseudomembranes in the colon (arrow). Histological findings (hematoxylin and eosin [HE] stain) revealed extensive, severe, acute pseudomembranous colitis with acute cryptitis, crypt abscesses, and mucosal ulceration, consistent with C. difficile colitis (C).
Tetsuro Ohba et al. JBJS Case Connect 2011;1:e2
©2011 by The Journal of Bone and Joint Surgery, Inc.

5. Polymerase chain reaction (PCR) testing of DNA extracted from mucosal debris revealed positive findings for C. difficile toxin B (tcd B) (arrow).
Polymerase chain reaction (PCR) testing of DNA extracted from mucosal debris revealed positive findings for C. difficile toxin B (tcd B) (arrow).
Tetsuro Ohba et al. JBJS Case Connect 2011;1:e2
©2011 by The Journal of Bone and Joint Surgery, Inc.