4. 1.When do cells use it? a)____________ b)____________ c)____________ 2.Cell that reproduce by asexual reproduction reproduce constantly.

5. 1.Division of ____________ __________(body) 2.Process in which the nucleus divides to form 2 new nuclei Somatic Cell Daughter Cells Performed by a single (parent) cell

7. 1.____________ structure of DNA in the cell 2.Located in the ____________ 3.Usually are uncoiled in the form of ____________ 4.Only ____________ when the cell divides and the chromatin condenses 5.Held together by a ____________

9. (do not write) Interphase Prophase Metaphase Anaphase Telophase **Animated Video**Animated Video

10. Prior & After Mitosis ____________ ____________ – ____________ % of cell life spent here – Cell goes about it’s business ____________ ____________ – DNA is duplicated ____________ ____________ – Cell prepares to divide Cannot see DNA- uncoiled as ____________

12. DNA becomes ____________ as ____________ Nuclear membrane ____________ ____________ migrate to opposite poles Spindle fibers ____________ Easy to remember- Prophase- prepares for mitosis

14. Spindle fibers ____________ to centromeres Chromosomes ____________ at midline of the cell Easy to remember- metaphase, DNA at middle

16. Spindle fibers ____________ centromeres One chromatid goes to each ____________ (they look like V’s) Easy to remember- anaphase, away they go

18. Chromatids reach ____________ Mitosis ends when new ____________ ____________ form Some evidence of cell dividing Easy to remember- telophase, terminal phase

20. Division of ____________ Technically not in mitosis – Animal cell- pinching of cell membrane- cleavage – Plant cell- formation of new cell wall- cell plate – DNA becomes non-visible, back to chromatin Daughter cells enter G1 period of interphase

23. Cells with a complete set of chromosomes called diploids Humans have 46 chromosomes or 23 pairs of chromosomes Human diploid # = 23 Most cells are diploid

24. Uncontrollable mitosis (no G1) – Cells cease to do what they are supposed to be doing in favor of dividing. Cancer does not “poison” your body…

25. 1951, a poor 31 Year old African American mother of 4 was dying of cervical cancer @ Johns Hopkins Hospital – Dr. George Gey- sampled some of the cancerous cells, found they could live indefinitely and multiply outside the body – She died 6 months later, but cells still live on HeLa cells – Used to study many different diseases – Polio Vaccine – How to transport cells

26. First, lets watch: University of Madison Mitosis Shuffle Your turn! “The Hustle” by Van McCoy