1. USFD activity in WP11 NND Internal Review/USFD-CISTIB/February 2015 Method developed for DXA and delivered in D11.1. Volumetric mesh shape and intensity model

2. USFD activity in WP11 NND Internal Review/USFD-CISTIB/February 2015 Method developed for DXA and delivered in D11.1. Statistical Shape Model

3. USFD activity in WP11 NND Internal Review/USFD-CISTIB/February 2015 Method developed for DXA and delivered in D11.1. MRI – DXA intensity matching

4. USFD activity in WP11 NND Internal Review/USFD-CISTIB/February 2015 Method developed for DXA and delivered in D11.1. DXA discontinued afterwards

5. USFD activity in WP11 NND Internal Review/USFD-CISTIB/February 2015 USFD task redefinition.

6. NND Internal Review/USFD-CISTIB/February 2014 Joint center and axis Sphere and/or cylinder fitted to the SSM reconstruction. 6

7. NND Internal Review/USFD-CISTIB/February 2015 Ligament insertion points Extrapolated from bones and muscles shape. Morphing of template model including insertion points. 7

8. NND Internal Review/USFD-CISTIB/February 2015 Muscle volume and PCSA Extract muscles centerline and cross-sectional area from muscle shape. 8

9. USFD activity in WP11 NND Internal Review/USFD-CISTIB/February 2015 Building complete geometric model:

10. From imaging data to modeling parameters: Well established protocol. Meshes in stl format. From modeling parameters to OpenSim: Format of parameters being fixed. – Next step: Send mock-up parameters – Major activity for understanding the segment frames. Knee joint description: – Real dynamics: Non-cylindrical – Segment frame definition: axis lateral-medial epicondyle 10 USFD activity in WP11

11. NND Internal Review/USFD-CISTIB/February 2015 Segment frame definition: Lateral epicondolyte Medial epicondolyte