1. Ostium Secundum Atrial Septal Defect Closure Thomas Hoy February 11, 2004 Department of Biomedical Engineering BME 272 Senior Design

2. Project Definition Goals in February Goals in February Pick final project designPick final project design Begin patent search on chosen designBegin patent search on chosen design Project Goals Project Goals less costly / more simplistic occlusion device for an ASDless costly / more simplistic occlusion device for an ASD Develop a device that is easily sized to the ASDDevelop a device that is easily sized to the ASD Ensure ease use in the medical environmentEnsure ease use in the medical environment Ultimately improve the quality of life of the patient.Ultimately improve the quality of life of the patient.

3. Overall Project Status Research portion is near completion Research portion is near completion Final design decision pending advisor’s approval Patent search on the possible design models

4. Project Background What is a Ostium Secundum Atrial Septal Defect? What is a Ostium Secundum Atrial Septal Defect? congenital heart disease causes left to right shunting across interatrial septum Why should we care? Why should we care? Isolated secundum atrial septal defects of significance occur in approximately 70,000-100,000 individuals today. OSASD constitutes approx. 7-10% of all cases of CHD. 32,000 infants (one out of every 125 to 150)

5. Current Status Have updated website Have updated website http://vubme.vuse.vanderbilt.edu/king/srdesig n/2003/group22http://vubme.vuse.vanderbilt.edu/king/srdesig n/2003/group22http://vubme.vuse.vanderbilt.edu/king/srdesig n/2003/group22http://vubme.vuse.vanderbilt.edu/king/srdesig n/2003/group22 Compiled listing of all major occlusion devices (purpose, costs, methods, design) Compiled listing of all major occlusion devices (purpose, costs, methods, design) Final design ideas Final design ideas Configuration of Helix designConfiguration of Helix design Petal designPetal design

6. Key Issues Must remain simplistic Must remain simplistic Main focus is on the locking mechanism Main focus is on the locking mechanism Materials to use in design Materials to use in design Design of the ‘memory’ frame Design of the ‘memory’ frame

7. Future Work Pick final design to focus upon Pick final design to focus upon Determine materials that will be included in design Determine materials that will be included in design Update webpage Update webpage Work on locking mechanism Work on locking mechanism