1. IMRT

3. 3DCRT vs IMRT Treated Volume Tumor Target Volume Intensity Modulation Treated Volume Critical structure Target Volume Collimator "Classical" Conformation IMRT Critical structure Great for treating donuts and bananas

4. PTV RO IMRT

5. IMRT VS PROTONS Ethmoid Upper Abdomen Brain

6. Expanding the Horizon Phase 1 Physical Conformality Phase 1 Physical Conformality Phase 2 Biological Conformality Phase 2 Biological Conformality Phase 3 Multi-Dimensional Phase 3 Multi-Dimensional Conformal Radiotherapy Conformal Radiotherapy 1990 200 0 2005-….

7. PET CT PET/CT

8. IMAGE FUSION FOR IMRT CT GTV (red contour) PET GTV (yellow contour) PET/CT GTV (red contour)

10. HYPOXIA: [ 18 F]FAZA (Nitroimodazole) PET/CT 60 y male Hypopharyngeal SCC T/B ratio 3.2 PET/CT Fusion 4 h after inj. sagcoraxial Piert et al., TUM CT