1. Hormones that Affect Metabolism

2. Two Major Glands Thyroid Gland Parathyroid Gland

3. Thyroid Gland Thyroxine (T4) Triiodothyronine (T3) –Both need iodine to be made. –Used to oxidize sugar and other nutrients. –More T4 in the blood will “boost metabolism”

4. Hypothyroid or Hyperthyroid If the thyroid gland produces T4 and T3, hormones that regulate metabolism, what would happen if: a)The thyroid stopped producing T4 and T3? (hypothyroidism) b)The thyroid could not stop producing T4 and T3? (hyperthyroidism)

5. Calcitonin Calcitonin is also released by the thyroid, and it counter-acts parathyroid hormone (PTH) by: Inhibiting Ca 2+ absorption by the intestines Inhibits Ca 2+ reabsorption in the nephrons of the kidney

6. Thyroid Negative Feedback Loop

7. Acronyms: TRH – Thyroid Releasing Hormone TSH – Thyroid Stimulating Hormone

8. What happens if the body lacks iodine?

9. Goiter

10. Parathyroid Glands Four groups of cells on the thyroid gland. Release a hormone called parathyroid hormone, or “PTH”. –PTH raises the calcium levels in the blood.

11. Negative Feedback

12. Human Growth Hormone (HGH) Too much? - Giantism Too little? - Dwarfism Produced in and released from the anterior pituitary gland. Famous Example: How did Andre the Giant die?

13. Human Growth Hormone Cause cells to grow in size and in number. Promotes protein synthesis. Promotes the breakdown of fats. –↑ GH, muscles use fatty acids as energy –Loss of fat during growth spurts

14. Growth Hormone Doping? Some athletes believe that taking human growth hormone supplements will increase their athletic performance. –In small groups, look up the practice of “doping” with human growth hormone. Come to a consensus about whether or not this practice is safe. Be prepared to back up your stance with evidence.