1. Diagnostics – Periferals Analytical 920 LCSemi-Prep 940 LC

2. Modules

3. Fraction Collector Problems Movement Problems X, Theta and Z Movement Problems Communication Problems Self Test Sequence LED’s on Fraction Collector Electronics Problems Error Codes in Software

4. Column Heater/ Manual Injector Problems General Issues Heating Problems Communications Leaks Pressure

5. Scale Up Module Problems General Issues Leaks Pressure

6. MIB Problems General Issues Communications Power

7. IMS Fraction Collector Actions & Tests Divert valve replaced Tube Access Accuracy and Timing Test

8. IMS Column Heater/ Manual Injector Actions & Tests Injector valve stator replaced Injector valve rotor replaced Column valve stator replaced Column valve rotor replaced Column heater temperature accuracy and stability

9. IMS Scale Up Module Actions & Tests Injector valve stator replaced (SUM) Injector valve rotor replaced (SUM) Column valve stator replaced (SUM) Column valve rotor replaced (SUM)

10. IMS MIB Actions & Tests Backup the system configuration to a local folder Restore the system configuration from a previous backup Instrument Error Log Full System Test

11. Fraction Collector Practical Person 1: Replacement of X Encoder PCB, X Stepper Motor, X Timing Belt, Removal and Installation of Covers Person 2: Replacement of Theta Encoder PCB, Theta Stepper Motor, Power Supply Person 3: Replacement of Z Encoder PCB, Z Stepper Motor, Z Timing Belt, Z Shafts Replacement of Main PCB and Encoder Wheel Alignment

12. Heater/ Manual Injector & MIB Practical Person 1: Replacement of the Injector Valve Rotor and Stator Replacement of the Column Valve Rotor and Stator Person 2: Column heater temperature accuracy and stability Test Person 3: Perform a Backup and Restore on the MIB All: Perform a full system test

13. SUM & MIB Practical Person 1: Replacement of the Injector Valve Rotor and Stator Replacement of the Column Valve Rotor and Stator Person 2: Replacement of the Manual Injector Valve Rotor and Stator Person 3: Perform a Backup and Restore on the MIB All: Perform a full system test