1. An Introduction to Polymers Dr. Sheppard CHEM 4201 Fall 2014

2. Polymers Natural vs. synthetic Industries What is a polymer? Monomer Dimer Oligomer Polymer Copolymer

3. Crosslinked Dendrimers Structure Linear Branched

4. Copolymers

5. Properties Structure Size and MW Density Crystallinity Strength Biodegradability Example: polyethylene

6. Polymer recycling

7. Polymer Classifications Thermal Properties Thermoplastics Plasticizers Thermoset plastics

8. Polymer Classifications Uses Elastomers (rubber) Fibers Adhesives Natural rubber

9. Polymer Classifications Method of Synthesis 1. Chain-growth/addition polymerization 2. Step-growth/condensation polymerization

10. Polymerization Reactions 1. Chain-growth/addition Radical

11. Polymerization Reactions 1. Chain-growth/addition Acid (cationic) Base (anionic)

12. Polymerization Reactions 2. Step-growth/condensation

13. Naming Simple polymers:

14. Some Addition Polymers Polytetrafluoroethylene (PTFE) 1,1-Dichloroethylene Polypropylene (PP)

15. Some Addition Polymers Acrylates Poly(methyl methacrylate) (PMMA) Poly(ethyl acrylate) (PEA) Poly(2-hydroxyethyl methacrylate) Cyanoacrylates

16. Some Addition Polymers Rubber Natural rubber Neoprene rubber Butadiene copolymers

17. Polyamides Nylon 6,6 Nylon 6 Some Condensation Polymers

18. Polyamides Kevlar

19. Some Condensation Polymers Polyesters Poly(ethylene terephthalate) Other polyesters

20. Some Condensation Polymers Polyurethanes Spandex Other polyurethanes

21. Polycarbonates Lexan Some Condensation Polymers

22. Silicones (Siloxanes)

23. Applications of Polymers Choosing a polymer Design Other factors Mechanical/thermal properties Synthesis Body’s reaction to polymer Biodegradability Polyglycolide (PGA), polylactide (PLA), and copolymers

24. Drug-polymer conjugate http://www.neurospine.com/ brain_gliadel.htm http://www.neurospine.com/ brain_gliadel.htm http://www.moffitt.org/File%2 0Library/Main%20Nav/Rese arch%20and%20Clinical%20 Trials/Cancer%20Control%2 0Journal/v5n2/article4.pdf http://www.moffitt.org/File%2 0Library/Main%20Nav/Rese arch%20and%20Clinical%20 Trials/Cancer%20Control%2 0Journal/v5n2/article4.pdf Biodegradable Polymers for Drug Delivery Drug linker polymer