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By:Chuck Purcell.  Drug Name:Fluoxetine  Brand Names: Prozac,RECONCILE,Rapiflux,Sarafem  Chemical Name:N-methyl-3-phenyl-3-[4- (trifluoromethyl)phenoxy]propan-1-amine.

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Presentation on theme: "By:Chuck Purcell.  Drug Name:Fluoxetine  Brand Names: Prozac,RECONCILE,Rapiflux,Sarafem  Chemical Name:N-methyl-3-phenyl-3-[4- (trifluoromethyl)phenoxy]propan-1-amine."— Presentation transcript:

1 By:Chuck Purcell

2  Drug Name:Fluoxetine  Brand Names: Prozac,RECONCILE,Rapiflux,Sarafem  Chemical Name:N-methyl-3-phenyl-3-[4- (trifluoromethyl)phenoxy]propan-1-amine

3  Prozac is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Prozac affects chemicals in the brain that may become unbalanced and cause depression, panic, anxiety, or obsessive-compulsive symptoms.

4  Eli Lilly and Company in 1970  David Wong, proposed to retest the series for the in vitro reuptake of serotonin, norepinephrine and dopamine.  Trade name Prozac, in February 1977  Eli Lilly's patent on Prozac (fluoxetine) expired in the United States in August 2001,prompting an influx of generic drugs onto the market.

5  used to treat depression  obsessive-compulsive disorder  some eating disorders  panic attacks.  Also treats symptoms of premenstrual dysphoric disorder, including mood swings, irritability, bloating, and breast tenderness.

6

7 Temporary:  Euphoria  Calmness  Happiness  Alertness

8  nervousness  nausea  dry mouth  sore throat  drowsiness  weakness  uncontrollable shaking of a part of the body  loss of appetite  weight loss  changes in sex drive or ability  excessive sweating

9  rash  hives  fever  joint pain  swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs  difficulty breathing or swallowing  fever, sweating, confusion, fast or irregular heartbeat, and severe muscle stiffness  seeing things or hearing voices that do not exist (hallucinating)  seizures  withdrawl

10  http://www.rxlist.com/prozac-drug.htm#cp http://www.rxlist.com/prozac-drug.htm#cp  http://www.ncbi.nlm.nih.gov/pubmedhealth/ PMH0000885/ http://www.ncbi.nlm.nih.gov/pubmedhealth/ PMH0000885/  http://www.merckmanuals.com/professional /lexicomp/fluoxetine.html#NA7E33 http://www.merckmanuals.com/professional /lexicomp/fluoxetine.html#NA7E33  http://www.merckmanuals.com/professional /lexicomp/fluoxetine.html#NA7E33 http://www.merckmanuals.com/professional /lexicomp/fluoxetine.html#NA7E33  http://drugtopics.modernmedicine.com/drug topics/data/articlestandard//drugtopics/072 008/491207/article.pdf


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