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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Cardiovascular Dysfunction
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Fetal Circulation Structures Umbilical vein; umbilical arteries Foramen ovale Ductus arteriosus Ductus venosus
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Changes at Birth
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Pediatric Indicators of Cardiac Dysfunction Poor feeding Tachypnea/ tachycardia Failure to thrive/poor weight gain/activity intolerance Developmental delays + Prenatal history + Family history of cardiac disease
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Two Types of Cardiac Defects Congenital –Anatomic>abnormal function Acquired –Disease process Infection Autoimmune response Environmental factors Familial tendencies
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Causes of CHD Chromosomal/genetic = 10%-12% Maternal or environmental = 1%-2% –Maternal drug use Fetal alcohol syndrome—50% have CHD –Maternal illness Rubella in 1st 7 wks of pregnancy→50% risk of defects including PDA and pulmonary branch stenosis CMV, toxoplasmosis, other viral illnesses>> cardiac defects IDMs = 10% risk of CHD (VSD, cardiomyopathy, TGA most common) Multifactorial = 85%
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. CHD Incidence: 5-8 per 1000 live births –About 2-3 of these are symptomatic in first year of life –Major cause of death in first year of life (after prematurity) –Most common anomaly is VSD –28% of kids with CHD have another recognized anomaly (trisomy 21, 13, 18, +++ )
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Older Classifications of CHD Acyanotic –May become cyanotic Cyanotic –May be pink –May develop CHF
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Newer Classification of CHD Hemodynamic characteristics –Increased pulmonary blood flow –Decreased pulmonary blood flow –Obstruction of blood flow out of the heart –Mixed blood flow
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Increased Pulmonary Blood Flow Defects Abnormal connection between two sides of heart –Either the septum or the great vessels Increased blood volume on right side of heart Increased pulmonary blood flow Decreased systemic blood flow
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Increased Pulmonary Blood Flow Defects Atrial septal defect Ventricular septal defect Patent ductus arteriosus
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. ASD
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. VSD
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. PDA
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Obstructive Defects Coarctation of the aorta Aortic stenosis Pulmonic stenosis
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Coarctation of the Aorta
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Aortic Stenosis
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Pulmonic Stenosis and Catheter Placement
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Decreased Pulmonary Blood Flow Defects
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Tetralogy of Fallot
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Tricuspid Atresia
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Mixed Defects Transposition of great vessels Total anomalous pulmonary venous connection Hypoplastic heart syndrome –Right –Left
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Transposition of Great Vessels
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Normal Heart
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Totally Anomalous Pulmonary Venous Connection
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Hypoplastic Left Heart
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. CHF in Children Impaired myocardial function –Tachycardia, fatigue, weakness, restless, pale, cool extremities, decreased BP, decreased urine output Pulmonary congestion –Tachypnea, dyspnea, respiratory distress, exercise intolerance, cyanosis Systemic venous congestion –Peripheral and periorbital edema, weight gain, ascites, hepatomegaly, neck vein distention
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Interventional Cardiac Catheter Procedures in Children Transposition of great vessels Some complex single-ventricle defects ASD Pulmonary artery stenosis
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. INTERVENTION Balloon dilation DIAGNOSIS Valvular pulmonic stenosis Recurrent coarctation of aorta Congenital mitral stenosis Interventional Cardiac Catheter Procedures in Children (cont’d)
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Surgical Interventions Open heart Closed heart procedures Staged procedures Prepare child and family for procedures
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Postpericardiotomy Syndrome Symptoms: fever, pericardial friction rub, pericardial and pleural effusion Occurs in immediate postoperative period Also can occur later (postoperative day 7-21) Etiology unknown Theories of etiology –Viral infection; auto immune response; reaction to blood in pericardium –May require pericardiocentesis or pleurocentesis
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Acquired Cardiovascular Disorders Infectious and Inflammatory Cardiac Disorders
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Endocarditis BE, IE, or SBE Strep Staph Fungal infections PROPHYLAXIS: 1 hr before procedures (IV) or may use PO in some cases
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Rheumatic Fever Rheumatic Heart Disease RF –Inflammatory disease occurs after Group A –ß-hemolytic streptococcal pharyngitis –Infrequently seen in U.S.; big problem in Third World –Self-limiting Affects joints, skin, brain, serous surfaces, and heart Rheumatic heart disease –Most common complication of RF –Damage to valves as result of RF
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Clinical Manifestations of RF Carditis Polyarthritis Erythema marginatum Subcutaneous nodules
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Prevention of RHD Treatment of streptococcal tonsillitis/pharyngitis –Penicillin G—IM X 1 –Penicillin V—Oral X 10 days –Sulfa—Oral X 10 days –Erythromycin (if allergic to above)—Oral X 10 days Treatment of recurrent RF –Same as above
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Kawasaki Disease A condition that causes inflammation in the walls of small- and medium-sized arteries throughout the body, including the coronary arteries. Heart complications may include: Heart complications include: Vasculitis, myocarditis, arrhythmia, and pericarditis.
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Kawasaki Disease— Treatment Then 3-5 mg/kg/day—antiplatelet IVIG ASA 80-100 mg/kg/day—fever
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Systemic Hypertension Primary: No known cause Secondary: Identifiable cause Pediatrics: HTN generally secondary to structural abnormality or underlying pathology –Renal disease –CV disease –Endocrine or neurologic disorders
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. BP Screenings for Children
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Hyperlipidemia Identify kids at risk and treat early Treatment: dietary –Restrict intake of cholesterol and fats If no response to diet→Rx –colestipol (Colestid) –cholestyramine (Questran)
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Pharmacology Iv IgG Digoxin/lanoxin ACE inhibitors ASA, NSAIDs Lasix Spironolactone (Aldactone)
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Heart Transplantation Orthotopic transplant Heterotopic transplant (piggyback) Organ donation issues Nursing considerations
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Anaphylaxis Definition Clinical manifestations Therapeutic management Nursing considerations
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Mosby items and derived items © 2005, 2001 by Mosby, Inc. Toxic Shock Syndrome (TSS) Diagnostic evaluation Therapeutic management Nursing considerations Criteria for definition of TSS
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