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Highlights of the Day: LYMPHOMA Presented By Sonali Smith at 2014 ASCO Annual Meeting.

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Presentation on theme: "Highlights of the Day: LYMPHOMA Presented By Sonali Smith at 2014 ASCO Annual Meeting."— Presentation transcript:

1 Highlights of the Day: LYMPHOMA Presented By Sonali Smith at 2014 ASCO Annual Meeting

2 Abstracts Presented By Sonali Smith at 2014 ASCO Annual Meeting

3 Diffuse Large B-cell Lymphoma: How can we improve on R-CHOP? Presented By Sonali Smith at 2014 ASCO Annual Meeting

4 Slide 4 Presented By Sonali Smith at 2014 ASCO Annual Meeting

5 Rituximab clearance by age and gender and study design Presented By Sonali Smith at 2014 ASCO Annual Meeting

6 Slide 6 Presented By Sonali Smith at 2014 ASCO Annual Meeting

7 Slide 7 Presented By Sonali Smith at 2014 ASCO Annual Meeting

8 Diffuse Large B-cell Lymphoma: How can we improve on R-CHOP? Presented By Sonali Smith at 2014 ASCO Annual Meeting

9 Synthetic lethality of lenalidomide in ABC-DLBCL and clinical proof of principle Presented By Sonali Smith at 2014 ASCO Annual Meeting

10 PFS by GCB vs. non-GCB Subtype* in RCHOP Case-matched Control and R2CHOP Patients Presented By Sonali Smith at 2014 ASCO Annual Meeting

11 OS by GCB vs. non-GCB Subtype in RCHOP Case-matched Control and R2CHOP Patients Presented By Sonali Smith at 2014 ASCO Annual Meeting

12 PFS by Treatment Type in GCB vs. non-GCB Subtype Presented By Sonali Smith at 2014 ASCO Annual Meeting

13 Abstracts Presented By Sonali Smith at 2014 ASCO Annual Meeting

14 FL survival is improving for most patients Presented By Sonali Smith at 2014 ASCO Annual Meeting

15 Abstract 8502: 246 patients with reviewed postinduction PET-CT Presented By Sonali Smith at 2014 ASCO Annual Meeting

16 CT & BM based response (IWC 1999 criteria) Presented By Sonali Smith at 2014 ASCO Annual Meeting

17 Both PET cut-offs predictive of PFS Presented By Sonali Smith at 2014 ASCO Annual Meeting

18 Postinduction PET status (cut-off ≥4) and Overall Survival Presented By Sonali Smith at 2014 ASCO Annual Meeting

19 Abstracts Presented By Sonali Smith at 2014 ASCO Annual Meeting

20 Mantle Cell Lymphoma 2014 Presented By Sonali Smith at 2014 ASCO Annual Meeting

21 CHOP ± Rituximab in MCL: Progression-Free Survival Presented By Sonali Smith at 2014 ASCO Annual Meeting

22 Approved agents for R/R MCL (Variable intensity of prior Rx among studies) Presented By Sonali Smith at 2014 ASCO Annual Meeting

23 LYM-3002: Replace vincristine with bortezomib Presented By Sonali Smith at 2014 ASCO Annual Meeting

24 Superior PFS by IRC with VR-CAP vs R-CHOP: 59% improvement Presented By Sonali Smith at 2014 ASCO Annual Meeting

25 Peripheral Neuropathy Presented By Sonali Smith at 2014 ASCO Annual Meeting

26 Conclusions – Efficacy Presented By Sonali Smith at 2014 ASCO Annual Meeting

27 Abstracts Presented By Sonali Smith at 2014 ASCO Annual Meeting

28 Take-home points Presented By Sonali Smith at 2014 ASCO Annual Meeting


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