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Supplementary Materials. Figure S1 – (a) ISDD Model simulations for TNP in 6-well and 96-well plates. (b) Corresponding time-weighted average (TWA) factor.

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Presentation on theme: "Supplementary Materials. Figure S1 – (a) ISDD Model simulations for TNP in 6-well and 96-well plates. (b) Corresponding time-weighted average (TWA) factor."— Presentation transcript:

1 Supplementary Materials

2 Figure S1 – (a) ISDD Model simulations for TNP in 6-well and 96-well plates. (b) Corresponding time-weighted average (TWA) factor [insert: lower incubation times]. (c, d) Time-weighted average dosage (TWAD) for 2 and 24 hours against the absolute exposure for (c) 96-well plate format and (d) 6-well plate format (different units are used for TWAD to fit into plot area).

3 Table S1: Some examples of the TWA factor and TWAD values used. Format 6-well plate 96-well plate TimeTWA Factor TWAD (AE: 50 ugcm -2 )TWA Factor TWAD (AE: 100 ugcm -2 ) 0.250.00940.0494740.00321 0.50.0360.1894740.01213.78125 10.14090.7415790.047514.84375 20.55712.9321050.187758.65625 42.183411.491580.7465233.2813 86.180632.529472.9769930.2813 1210.177153.563686.60862065.188 1614.172474.5915810.60823315.063 2018.166395.6121114.60774564.906 2422.157116.615818.60115812.844

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