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Klinik und Poliklinik für Augenheilkunde All authors have no financial interest in the subject matter of this poster. R. Khoramnia, J. P. Salgado, C.P.

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Presentation on theme: "Klinik und Poliklinik für Augenheilkunde All authors have no financial interest in the subject matter of this poster. R. Khoramnia, J. P. Salgado, C.P."— Presentation transcript:

1 Klinik und Poliklinik für Augenheilkunde All authors have no financial interest in the subject matter of this poster. R. Khoramnia, J. P. Salgado, C.P. Lohmann, C. Winkler von Mohrenfels ASCRS 2011 Comparison Between Central Corneal Thickness Measurements in Healthy Eyes Using a New Device and 2 Other Methods

2 Purpose Klinik und Poliklinik für Augenheilkunde The TMS-5 (Tomey) is a new device for the examination of the anterior eye segment combining Placido- and Scheimpflug-Technology. The purpose of this study was to compare central corneal thickness (CCT) measurements using TMS-5, LenStar/Allegro Biograph (Haag-Streit/WaveLight), and the gold standard ultrasonic pachymetry (Pachymeter SP-3000, Tomey). TMS-5 Foto: www.ophthalworld.de Allegro Biograph/LenStar Foto: www.wavelight.com SP-3000 Foto: www.eyenovation.de

3 Material and methods Klinik und Poliklinik für Augenheilkunde 48 eyes of 24 healthy volunteers were included in this comparative study. In all eyes, CCT was measured with the TMS-5 (Tomey, Nagoya, Japan), LenStar (Haag-Streit AG, Koeniz, Switzerland)/Allegro Biograph (WaveLight AG, Erlangen, Germany), and ultrasonic pachymetry (Pachymeter SP-3000, Tomey, Nagoya, Japan). The values obtained from the different devices were compared using Bland-Altman plots and linear regression.

4 Results I Klinik und Poliklinik für Augenheilkunde The mean CCT readings with the TMS-5, LenStar/Allegro Biograph, and ultrasound were 516.6 µm, 535.7 µm, and 543.6 µm, respectively. Regression analysis showed a high correlation between the values obtained with the TMS-5 and the LenStar/Allegro Biograph (r=0.950, p<0.001) and the values obtained with the TMS-5 and ultrasound (r=0.918, p<0.001).

5 Results II Klinik und Poliklinik für Augenheilkunde Compared to the LenStar/Allegro Biograph and ultrasound, the TMS-5 underestimated the CCT. The mean differences were -19.1 µm compared to the LenStar/Allegro Biograph and -27.0 µm compared to ultrasound as shown in the Bland-Altman plots.

6 Conclusion Klinik und Poliklinik für Augenheilkunde Regression analysis showed a high correlation between the values obtained with the TMS-5 and the LenStar/Allegro Biograph and the values obtained with the TMS-5 and ultrasound. However, the TMS-5 underestimated the CCT compared to the LenStar/Allegro Biograph and ultrasound. Therefore, the TMS-5, LenStar/Allegro Biograph, and ultrasound should not be used interchangeably for the measurement of CCT.

7 Name der Klinik Klinik und Poliklinik für Augenheilkunde Contact: Klinikum rechts der IsarTel.: +49 89 4140 – 2310 Technische Universität MünchenFax: +49 89 4140 – 4076 Klinik und Poliklinik für AugenheilkundeEmail: augenklinik@lrz.tum.de Ismaninger Str. 22www.med.tum.de 81675 Munichwww.augenklinik.med.tum.de GERMANY

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