1. 5 ft 3 V-blender w/ Spectrometer Brimrose 5030 wireless process spectrometer collection parameters: Spectra are collected once every rotation at 23 rpm Tilt sensor triggers spectrometer about 10° before bottom 12 spectra are collected and averaged every rotation Collection time is 0.45 sec or 62° for 12 spectra 62°on off

2. Tablet Validation V-Blend MgSt Dispersion 5 mg 2 ft 3 V-blending for 6 minutes

3. Tablet Validation V-Blend MgSt Dispersion 2 ft 3 V-blending for 6 minutes 5 mg

4. Blend Monitoring-NIR Process Spectrometer Romaco blender lid w/ Brimrose 4030 spectrometer mount and sapphire window

5. Tablet Validation Final Blend Dotted line represents theoretical MgSt w% of 0.84% 1500L Bin Tumbled for 5 min 15 mg

6. Tablet Validation Final Blend 1500L Bin Tumbled for 5 min 15 mg

7. 200 ft 3 Double Cone Blender outfitted with Brimrose Luminar 4030 AOTF NIR Spectrometer Spectra are collected once every rotation at 13 rpm Tilt sensor triggers spectrometer about 10° before bottom 12 spectra are collected and averaged every rotation Collection time is 0.51 sec or 40° for 12 spectra 40° on off Brimrose 4030 wireless process spectrometer collection parameters: Use of NIR During Large Scale Blending

8. API Content in 200 ft 3 Double Cone, 13 RPM Target = 49% API Blending w/NIR Monitoring – Conc. & C.U. RSD Initial Blend CU RSD = 1.1% Model Parameters: Wavelengths 1-601 Sample 21-80 1 PC 1 st Derivative Gain = 1 API RSD in 200 ft 3 Double Cone, 13 RPM