1. Transient Tachypnea Of the Newborn

2. Transition to pulmonary respiration Adequate lung function is dependent on: airway patency functional lung development maturity of respiratory control fetal lung fluid must be removed and replaced with gas

3. active sodium transport across the pulmonary epithelium drives liquid from the lung into the interstitium and subsequently, to the vasculature Catecholamines, vasopressin, prolactin, glucocorticoids enhance lung fluid absorption

4. Transient Tachypnea of the Newborn Follows uneventful normal preterm or term vaginal or cesarian delivery Due to slow absorption of fetal lung fluid resulting in decreased pulmonary compliance and tidal volume and increased dead space

5. Clinical manifestations Early onset tachypnea Retractions Expiratory grunting Occasional cyanosis relieved by minimal oxygen (<40%) Lungs are usually clear, no rales or rhonchi

6. Radiologic findings prominent pulmonary vascular markings fluid in intralobar fissures overaeration flat diaphragms pleural effusion (rare)

7. Distinctive feature of TTN: Rapid recovery, usually within 3 days Treatment is supportive. No evidence for use of oral furosemide.