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Statistical Analysis of Mouse Gut Microbiota Alex Tran Computer Systems Lab 2009-2010
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Abstract The mouse gut microbiotal community is the population of bacteria, which inhabit the digestive track of a given population of mice. The ability to understand the microbiotal community has implications, which extend beyond mice and into factors of human obesity and the dietary needs of the human body. Computational genomics is an emerging field, which blends both biology and computer science, to analyze genes. This study seeks to utilize several methods emerging within computational genomics to analyze the gut microbiome of mice to observe the effects of varying diets on the gut microbiotal community, as well as create a universal and user friendly tool for researchers to utilize when studying any gut microbiome.
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Introduction Genomics Gut Microbiota Mouse Digestive Tract http://esd.lbl.gov/img/HOME/a_gut_feeling.jpg
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Background OB/OB mice Human Microbiome Project http://www.use.com/media/2008/0208/35680/p_001.jpg
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Development Python Tkinter I/O intensive http://tamago-club.cocolog- nifty.com/photos/uncategorized/piyo070219b-thumb.png
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Objectives User Friendliness Efficiency Universal Compatibility Hugenholtz RDP
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Current Status Shell GUI Reads standard format files Two taxonomic trees Ability to specify taxonomy used
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