1. AFAMS Various Drugs EO 003.01 Part 31

2. AFAMS Overview of Lesson (Insert Dari) Insert Dari Antidotes General Nutrients Contrast Media Other Therapeutic Products

3. AFAMS What I need to know as a pharmacy technician (Insert Dari) In this lecture we will cover the drugs listed in the ANA Formulary which are classified according to the ATC system under (V) Various Drugs For each of these medications/classes students must obtain an understanding of: (1) Mechanism of Action (2) Indications (Uses) (3) Efficacy (when applicable) (4) Side Effects (when applicable) Insert Dari

4. AFAMS

5. Antidotes (Insert Dari)

6. AFAMS All Other Therapeutic Products - Antidotes

7. AFAMS Mechanism of Action (Insert Dari) Flumazenil: prevents activity at the benzodiazepine receptor site Naloxone: competes and displaces opioids at opioid receptor sites. Indication (Uses) مورد استعمال Overdose Reverse side effect of benzodiazepenes (Flumazenil) Reverse side effect of narcotics (Naloxone) Used to wake a person up from surgery (flumazenil).

8. AFAMS Side Effects عوارض جانبی Naloxone: Dizziness Upset stomach Flumazenil: Dizziness Upset stomach Flushing Blurred eyesight Dry mouth *Both are administered but subcutaneous injection or intravenously*

9. AFAMS General Nutrients (Insert Dari)

10. AFAMS

11. Mechanism of Action (Insert Dari) Provides nutrition Increases caloric intake Indication (Uses) مورد استعمال Post surgery – unable to chew food to acquire nutrients Patients who are malnourished.

12. AFAMS Contrast Media (Insert Dari)

13. AFAMS

14. Mechanism of Action (Insert Dari) Indication (Uses) مورد استعمال Used to visualize anatomical structures during diagnostic imaging. Opacification of vessels and anatomical structures in the path of flow of the contrast media which allows for radiographic visualization.

15. AFAMS Side Effects عوارض جانبی Possible allergy symptoms including: rash hives, itching, red swollen blistered skin Dizziness Flushing Upset Stomach

16. AFAMS Other Therapeutic Agents (Insert Dari)

17. AFAMS

19. Mechanism of Action (Insert Dari) Stops nerve conduction preventing feeling or sensation in the area applied. Indication (Uses) مورد استعمال Oral and topical anesthetic (numbing agent). Used in minor procedures and dental work.

20. AFAMS Side Effects عوارض جانبی May cause irritation at the site of application.

21. AFAMS

22. Mechanism of Action (Insert Dari) Oral Herbal Supplement that is proposed to relax smooth muscle allowing easier passage of kidney stones. Also thought to help disintegrate kidney stones. Kidney stones. Indication (Uses) مورد استعمال

23. AFAMS Side Effects عوارض جانبی Mild gastrointestinal upset. There have been some studies showing a benefit to taking this medication, still more research needs to completed to fully understand the benefit of this product. Efficacy (Insert Dari)

24. AFAMS

25. Mechanism of Action (Insert Dari) Draws water into the bowel stimulating a bowel movement and thus emptying the bowel. Indication (Uses) مورد استعمال Given to patients to empty the bowel prior to a procedure.

26. AFAMS Side Effects عوارض جانبی Causes diarrhea and gastrointestinal upset. Works almost immediately. Efficacy (Insert Dari)

27. AFAMS

28. Mechanism of Action (Insert Dari) Kills bacteria and moulds Indication (Uses) مورد استعمال Disinfection of medical instruments Not for human use, do not ingest.

29. AFAMS Questions? (Insert Dari)

30. AFAMS In-class Assignment (Insert Dari) This assignment will consist of 3 questions which are to be completed individually. Once complete the instructor will review the answers with the class. Insert Dari

31. AFAMS 1. Which of the following drugs are antidotes? (Insert Dari) A)Flumazenil B)Iohexol C)Microenema D)Naloxone

32. AFAMS 1. Answer: Which of the following drugs are antidotes? (Insert Dari) A)Flumazenil B)Iohexol C)Microenema D)Naloxone

33. AFAMS 2. Match the following drugs with their indication (Insert Dari) A)Naloxone B)Iohexol C)Ensure D)Oxybupracaine (1)Contrast media (2)To provide nutrition (3)Antidote (4)Local anesthetic

34. AFAMS 2. Match the following drugs with their indication (Insert Dari) A)Naloxone (3) antidote B)Iohexol (1) contrast media C)Ensure (2) to provide nutrients D)Oxybupracaine (4) local anesthetic

35. AFAMS 3. Glutaraldehyde is suitable for human consumption, true or false? (Insert Dari)

36. AFAMS 3. Glutaraldehyde is suitable for human consumption, true or false? (Insert Dari) Answer: False, it is used for disinfecting medical instruments only. (Insert Dari)