1. Benign Metastasizing Leiomyoma

2. Female 58 years old Latin teacher in a French University Past history: 2003 hysterectomy for uterine leiomyomas ----------------------------------------------------- October 2010: abdominal pain CT scan 2013 09637 NK

3. October 2010 2013 09637 NK

4. Percutaneous biopsy in a Cancer Center: Leiomyomatosis Hormonal receptors + 2013 09637 NK

6. Double J catheter Aromatase inhibitor Treatment stopped by the patient in march 2013 because of its intolerance and worsening functional signs 2013 09637 NK

7. Sept 2013 (+ 3 years)

8. Surgery November 2013 Partial cystectomy: Enterocystoplasty Rectal resection (colo rectal anastomosis) Resection of the left external iliac vein Resection of part of vagina Resection of the nodule in the right iliac fossa 2013 09637 NK

9. Pathology Main mass: 29 X 20 X16, cystic Spindle-shaped smooth muscle cells 0 mitosis /10 HPF Necrosis < 50% KI 67: 1% Vagina and bladder infiltrated No intra luminal tumor in the left external iliac vein Benign Metastasizing Leiomyoma 1 Nodule 8 X 5 cm: idem 2013 09637 NK Desmin

10. Sept 2014 Asymptomatic No treatment