1. Cataract By Col Rana Intisarul Haq MCPS, FCPS (AFIO)

2. Lens The lens is a biconvex structure located directly behind the posterior chamber and pupil It is the lesser of the two refractive elements in the dioptric system The equatorial diameter in adult is about 9-10 mm The anteroposterior width of the lens is about 6 mm The lens has certain unusual features. It lacks innervation and is avascular.

3. Detail view of the anatomy of the eye

4. cataract Definition Any congenital or acquired opacity in the lens capsule or substance of the lens, irrespective of the effects on vision is called cataract.

5. Classification of Cataract According to Age According to Morphology According to Etiology According to maturity Congenital and acquired

6. 6 Age Related Senile Cataract Age related cataract is universal in persons over 70 years of age. Both sexes are involved equally. There is considerable genetic influence. Average age of onset of cataract is approximately 10 years earlier in tropical countries.

7. Age Related Cataracts senile Presenile Cataracts Diabetes Mellitus Myotonic Dystrophy Atopic Dermatitis Neurofibromatosis-2 Traumatic Cataract Direct Penetrating Injury Concussion Electric Shock & Lightening Ionizing Radiation

8. Toxic Cataracts Steroids Chlorpromazine Miotics Busulphan Amiodarone Gold Secondary Cataracts Ch Ant Uveitis Ac Congestive Glaucoma High Myopia Hereditary Fundus Dystrophy

9. According to Morphology Posterior Subcapsular Cataract Ant Subcapsualr Cataract Nuclear Cataract Cortical Cataract Mature Cataract

10. F This diagram illustrates the different morphological characteristics of cataract together with their depth and location within the lens. The following illustrations demonstrate clinical examples of these anatomical entities. CATARACT THE LENS

11. CLASSIFICATION ON BASIS OF MATURITY IMMATURE CATARACT MATURE HYPERMATURE MORGAGNIAN

12. Causes Hereditary Age DM Steroids UV Rays Poor Nutrition Smoking

13. Epidemiology Cataract surgery is the most commonly performed surgery in elderly patient Any Age Two peaks <10 Years >65 Years

14. Pathology Depends on type of Cataract Early Changes – tiny areas of liquefaction called morgagnian degeneration seen as cortical spokes Progress to involve entire cortex Later on homogeneous appearance

15. 15 Etiopathogenesis of Cataract Caused by degeneration and opacification of existing lens fibres, formation of aberrant fibres or deposition of other material in their place. Loss of transparency occurs because of abnormalities of lens protein and consequent disorganization of the lens fibres

16. 16 Etiopathogenesis of Cataract Any factor that disturbs the critical intra and extra cellular equilibrium of water and electrolytes or deranges the colloid system within the fibres causing opacification. Fibrous metaplasia of lens fibres occurs in complicated cataract. Epithelial cell necrosis occurring in angle closure glaucoma leads to focal opacification of the lens epithelium (Glaucomflecken)

17. 17 Etiopathogenesis of Cataract Abnormal products of metabolism, drugs or metals can be deposited in storage diseases (Febry), metabolic diseases (Wilson) and toxic reactions (Siderosis)

18. Nuclear Cataract

19. Mature Cataract

20. Hypermature Cataract

21. Traumatic Cataract(Penetrating Trauma)

22. Vossius Ring

23. PSC in Atopic Dermatitis

24. Congenital Cataract

25. Stellate PSC in Myotonic Dystrophy

26. Shield Anterior Subcapsular Cataract (Atopic Dermatitis)

27. PSC in Atopic Dermatitis

28. Progression of Steroid- induced Cataract

29. Anterior Subcapsular Opacities (Ch Ant Uveitis)

30. Adv Cataract & Posterior Synechiae (Ch Ant Uveitis)

31. 31 Symptoms of Cataract 1. Blurring of vision 2. Frequent change of glasses due to rapid change in refractive index of the lens 3. Painless, progressive, gradual diminution of vision due to reduction in transparency of the lens 4. Second sight or myopic shift in case of nuclear cataract causing index myopia, improving near vision.

32. 32 Symptoms of Cataract 5. Loss or marked diminution of vision in bright sunlight or bright light beam in central posterior sub-capsular cataract. 6. Monocular diplopia or polyopia in presence of cortical spoke opacities 7. Glare in posterior sub-capsular cortical cataract due to increased scattering of light

33. 33 Symptoms of Cataract 8. Colored haloes around the light as seen in cortical cataract due to irregular refractive index in different parts of the lens. 9. Color shift, reds are accentuated 10. Visual field loss, generalized reduction in sensitivity due to loss of transparency

34. 34 Signs of senile cataract Positive findings 1. Diminution of vision 2. Anterior chamber is shallow in cases of intumescent cataract and deep in cases of hypermature (shrunken) cataract 3. Tremulousness of iris in cases of hypermature shrunken cataract

35. 35 Signs of senile cataract 4. Lenticular opacity, grey or white opacity in lens. Iris shadow in immature cataract. No iris shadow in mature cataract 5. Morgagnian Cataract- is characterized by liquefied cortex, which is milky and nucleus is seen as brown mass, seen as semicircular line, altering its position with change in position of head

36. 36 Signs of senile cataract 6. Distant direct ophthalmoscopy will reveal black shadow against red background in cases of immature cataract.

37. Thank you

38. Management of Cataract

39. HISTORY Age of Onset Decreased Vision Painless, effecting daily routine? If the patient is bothered about his decreased vision. Trauma Any Ophthalmological Problems Drugs Intake Exposure to Radiations Systemic Diseases Skin disease, joint pains, etc. Family History

40. Examination GPE SYSTEMIC EXAMINATION OCULAR EXAMINATION VISUAL ACUITY ADNEXA CORNEA ANTERIOR CHAMBER PUPIL VITROUS RETINA

41. Investigations Blood Glucose ECG Chest x-rays (PA view) Blood Complete Picture Any specific relevant investigation (if indicated)

42. Indication for Surgery Visual Improvement When the patient is bothered. Medical Indications When cataract is adversely affecting the health of the eye e.g.: Phacolytic Glaucoma Intumescent Cataract Diabetic Retinopathy Cosmetic Indications To restore black pupil

43. Optimal Post Op Refraction If monocular correction is reqd. e.g. in contralateral dense or amblyopia best post op refraction is -1DS. If binocular correction is reqd difference between the two eyes should not be more than 3DS.

44. SURGICAL TECHNIQUES ICCE ECCE ECCE with posterior chamber IOL implant Phacoemulcification

45. ECCE

46. IOL Implantation

47. Phacoemulcification

48. Operative Complications Complications of Local Anaesthesia Retrobulbar Hemorrhage Perforation of the globe, optic nerve or sheath Operative Complications: Bridle Suture Perforation of the globe Stripping of Descemet’s Membrane Damage to ciliary body

49. Operative Complications(Contd) Rupture of the Posterior Capsule Capsular Rupture without Vitreous Loss Small Tear Large Tear or Zonular Tear Capsular Rupture with Vitreous Loss vitrectomy Posterior Loss of Lens Fragments Small Fragments Large Fragments

50. Nuclear Material in Vitreous

51. Operative Complications(Contd) Suprachoroidal Hemorrhage Source long or short ciliary artery Contributing Factors sudden in IOP coughing Valsalva Manoeuvre Vitreous Loss Sudden rise in B.P. Retrobulbar anaesthetic without adrenaline

52. Operative Complications(Contd) Suprachoroidal Hemorrhage(Contd) Presentation after lens delivery, progressive shallowing of anterior chamber, increased IOP & iris prolapse, vitreous extrusion, loss of red reflex. In severe cases all intraocular contents may be extruded Immediate Treatment Closure of the Incision Administration of Hyperosmotic Agent

53. Operative Complications(Contd) Suprachoroidal Hemorrhage(Contd) Subsequent Treatment Topical & Systemic Steroids Between 7 & 14 Day drainage of the blood, pars plana vitrectomy & air-fluid exchange

54. Early Post-Operative Complications Iris Prolapse Cause - inadequate suturing Complications - defective wound healing, ch ant uveitis, epithelial ingrowth, cystoid macular edema, excessive astigmatism. Treatment

55. Early Post-Operative Complications Striate Keratopathy Cause - damage to corneal endothelium Hyphema

56. Early Post-Operative Complications Acute Bacterial Endophthalmitis Pathogenesis Causative Organisms Staph Epidermidis, Staph Aureus, Pseudomonas sp etc Source of Infection Prevention Treatment of local infections of the Patients Preoperative instillation of Povidine-iodine Meticulous draping Technique Postoperative injection

57. Draping of Eyes

58. Early Post-Operative Complications Acute Bacterial Endophthalmitis(contd) Clinical Features severity Time Interval Staph Aureus - 1st to 3rd day Staph Epidermidis - 4rth to 10th day Differential Diagnosis Retained Lens Matter Toxic Reaction Difficult or Prolonged surgery

59. Fibrinous Exudation in Severe Acute Endophthalmitis

60. Small Hypopyon

61. Acute Bacterial Endophthalmitis(contd) Clinical Features Differential Diagnosis Retained Lens Matter Toxic Reaction Difficult or Prolonged surgery

62. Early Post-Operative Complications Acute Bacterial Endophthalmitis(contd) Management Identification of causative organism aqueous samples vitreous samples Antibiotics Vitrectomy Steroids Subsequent therapy

63. Late Post-Operative Complications Opacification of the Posterior Capsule Types Elschnig’s Pearls Capsular Fibrosis Indications for Treatment Visual Acuity Impaired Visualization of Fundus Monocular Diplopia or severe glare Nd:YAG Laser Capsulotomy Complications

64. Elschnig Pearls

65. Fibrosis of Posterior Capsule

66. Technique of Nd:YAG Laser capsulotomy

67. Late Post-Operative Complications Malposition of IOL Tilting Decentration Treatment Corneal Decompensation Causes Treatment

68. Late Post-Operative Complications Retinal Detachment Risk Factors Disruption of Posterior Capsule Vitreous Loss Lattice Degeneration Sunset Syndrome Cause Traetment

69. Late Post-Operative Complications Chronic Endophthalmitis Causative Organism Propionibacterium Acnes Staph Epidermidis Clinical Features Treatment Strategy steroids & antibiotics Removal of IOL, remaining cortex & entire capsular bag