1. Anatomy & Neurobiology ANA 812 Urinary System: Kidney, Ureter & Urinary Bladder Kelly Chewning Emily Furlow Phil Keeley Laura Ross

2. Anatomy & Neurobiology Slide #126 Kidney- Human (H&E) – 2X Minor Calyces Renal Papilla Papillary Duct Collecting Ducts

3. Anatomy & Neurobiology Slide #126 Kidney- Human (H&E) – 4X Medullary Rays Cortex Renal Corpuscle s

4. Anatomy & Neurobiology Slide #126 Kidney- Human (H&E) – 40X Renal Corpuscle Proximal Convoluted Tubule Distal Convoluted Tubule Macula Densa PCT DCT

5. Anatomy & Neurobiology Slide #127 Kidney – Monkey (H&E) – 2X Medulla Cortex

6. Anatomy & Neurobiology Slide #127 Kidney – Monkey (H&E) – 4X Arcuate artery Interlobular artery Cortex – Medullary Junction

7. Anatomy & Neurobiology Slide #126 Kidney – Human (H&E) – 40X Bowman’s (Filtration) Space Visceral Layer (Podocyte Layer) Bowman’s Capsule = Visceral + Parietal Layers Parietal Layer Vascular Pole Urinary Pole

8. Anatomy & Neurobiology Slide #126 Kidney – Human (H&E) – 40X Extraglomerular mesangial cells Afferent Arteriole Region of Juxtaglomerular Cells (line afferent arteriole)

9. Anatomy & Neurobiology Slide #128 Kidney – Monkey (H&E) – 40X Bowman’s (Filtration) Space Macula Densa Basement Membrane

10. Anatomy & Neurobiology Slide #127 Kidney – Monkey (H&E) – 60X Thin Loop of Henle Collecting Ducts

11. Anatomy & Neurobiology Slide #126 Kidney – Human (H&E) – 4X/40X Transitional epithelium

12. Anatomy & Neurobiology Slide #126 Kidney – Human (H&E) – 10X/40X Papillary Ducts Simple columnar epithelium

13. Anatomy & Neurobiology Slide #131 Ureter- Monkey (H&E) – 4X Transitional epithelium Lamina propria (fibroelastic CT) Smooth Muscle Adventitia (loose areolar CT)

14. Anatomy & Neurobiology Slide # 131 Ureter- Monkey (H&E) – 10X Smooth muscle: Inner layer longitudinal Outer layer circular (reverse of GIT) No distinct submucosa present in any ureter. Mucosa forms longitudinal folds

15. Anatomy & Neurobiology Slide #131 Ureter- Monkey (H&E) - 40X Why ureter transitional epithelium is so special: Its basal cells are columnar in shape, however… Most superficial cells are large and broad with dome-shaped surface facing the lumen.

16. Anatomy & Neurobiology Slide # 133 Urinary Bladder- Monkey (H&E) - 4X Detrusor Lamina propria (fibroelastic CT) Transitional Epithelium Adventitia (loose areolar CT) (except for fundus: serosa)

17. Anatomy & Neurobiology Slide # 133 Urinary Bladder- Monkey (H&E) – 4X Detrusor smooth muscle: Outer longitudinal Circular Inner longitudinal

18. Anatomy & Neurobiology Slide # 133 Urinary bladder- monkey (H&E) – 40X Like the ureter- the Transitional Epithelium is unique: Its basal cells are columnar in shape, however… Most superficial cells are large and broad with dome-shaped surface facing the lumen.

19. Anatomy & Neurobiology Slide # 133 Urinary Bladder- Monkey (H&E) – 10X Bladder is empty- mucous lining in folds. * The bladder has no distinct submucosa

20. Anatomy & Neurobiology Slide # 132 Female Urethra- Monkey (H&E) - 4X Adventitia (loose areolar CT) Smooth muscle Lamina propria (fibroelastic CT) Epithelial lining

21. Anatomy & Neurobiology Slide # 132 Female Urethra- Monkey (H&E) - 40 X Transitional epithelium  Pseudostratified columnar  Stratified squamous epithelium