1. HP Labs Escondido, CA Methanol and Ethanol Analysis/ J. Picker The Ultimate Gourmet Martini

2. HP Labs Escondido, CA Objective Analyze methanol and ethanol at 100-1000 ug/L or lower Use standard or modified EPA Methods Provide adequate Turnaround and pricing to meet client needs Make a profit

3. HP Labs Escondido, CA Warning Methanol is “wood alcohol” minimum lethal dose 1g/kg but toxic effects as low as 10g. toxicity is due to metabolic production of formic acid Ethanol is less toxic

4. HP Labs Escondido, CA Problems Very Poor purging efficiency (i.e., NO 5030/5035) Allowed Prep. Techniques  5031 Azeotropic distillation  5032 Vacuum distillation  5021 Equilibrium Headspace =nd  5041 VOST train = nd  Direct Inject

5. HP Labs Escondido, CA Problems II Low sensitivity on FID and MS Interferences by HCs and other compounds on FID

6. HP Labs Escondido, CA HP Labs’ Solution Direct Aqueous injection/EPA Method 8260B GC Column and conditions to separate MeOH, EtOH from water Stable Labeled isotope internal standards (CD 3 OH,CD 3 CH 2 OH) Modified with Selected Ion Monitoring Mass Spectrometry (SIM)

7. HP Labs Escondido, CA

11. Sample Preparation: water Sample Size 1 mL Add Labeled IS Solution Inject

12. HP Labs Escondido, CA Sample Preparation: Soil Ultrasonic extraction (EPA 3550) 10 g/10 mL Remove 1mL Add IS Inject

13. HP Labs Escondido, CA Detection Limits Water and Soil MDLs < 100 ug/L (ug/kg) EQLs 250 ug/L (ug/kg)

14. HP Labs Escondido, CA What This Means Methanol and Ethanol on site or off site Rapid turnaround All levels of QC Price as low as fixed base