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1 Chromosomes and Mitosis Chapter 1 Thompson and Thompson
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1 Chromosomal Basis of Heredity A gene is a unit of heredity Genes are carried on DNA DNA is contained within chromosomes as chromatin
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Chromosomes replicate during cell division
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The chromosome complement
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Chromosome analysis Cri Du Chat results from loss of a small piece of chromosome 5
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Gene Map
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Chromosome pairs
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Non-identical genes
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Sex chromosomes These determine the sex of an individual –Two X chromosomes make a female –One X and one Y a male
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Two types of Cell Division Cells divide for two reasons –To create genetically identical copies of themselves This is mitosis – To create gametes that contain half of the chromosomes of the original cell This is meiosis 46 23 23 23 23
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The Cell Cycle
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S phase Replication Condensation Schematic
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DNA replication Duplex DNA begins Replicating Replication bubbles merge creating two duplexes
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Mitosis
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The stages of Mitosis
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Prophase Detail
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Prometaphase
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Metaphase
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Anaphase
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Telophase
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The sum total of the process
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Karyotypes
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Chromosome Length
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Chromosome appearance
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