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Published byCharles Milton Richard Modified over 9 years ago
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Collection of miniaturized test sites of living entities (microarrays) arranged on a solid substrate that permits many tests to be performed at the same time in order to achieve higher throughput, speed, accuracy and smaller size. A biochip can perform thousands of biological reactions, such as decoding genes, in a few seconds. A unity between electronics and biology/medicine
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Bio + Chip = Biochip Bio: stands for any biological entity eg: protein, DNA Chip: a computer chip Biochip: a combination of biological entity and a computer. Genome chips, Microarrays.
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Merge Biology and Electronics to overcome the brick wall Learn from natural phenomena and improve the current medical technology 1980s was the first time Biological entities were put on nonliving substrate.
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Consists of two components : Transponder Reader
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Passive Biochip: No Batteries and energy of its own. The implantable biochip It has a very long life, up to 99 years, and no maintenance. Composed of Microchip Antenna coil Tuning capacitor Glass Capsule
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Computer Microchip: Stores the unique ID number. Using a nnn-nnn-nnn format, the chip has the capability of storing of over 70 trillion unique numbers.
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Antenna Coil: Primitive Radio antenna to receive and send signals from the reader. Made up of coil of copper wire around a ferrite or iron core.
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Tuning Capacitor: Capacitor stores small charge (1/1000 of Watt) sent by the reader. “Radio waves" are utilized to communicate between the transponder and reader, the capacitor is "tuned" to the same frequency as the reader.
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Glass Capsule: Made of biocompatible material such as soda lime glass, hermetically (air-tight) sealed, covered with Polypropylene polymer. The small capsule measuring 11 mm in length and 2 mm in diameter, about the size of an uncooked grain of rice.
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Transmits a small signal Charges the tuning capacitor Receives ID number transmitted by the transponder. Takes place very fast, in milliseconds. Displays the result in an LCD display. The reader can include a RS-232 port to attach a computer.
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Injected by a Hypodermic syringe beneath the skin. Injection is safe and simple, comparable to common vaccines. Anesthesia is not required nor recommended. Usually behind the neck in cats and dogs. The right hand and forehead in humans.
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DNA (Gene expression): Human Genome Project started in 1990 to study genomes Study of interactions of individual genes in an organism Biochips helped to dramatically accelerate the identification of the estimated 80,000 genes in human DNA.
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Faster diagnosis of diseases Medicine will improve People will live longer healthier lives. Biological warfare diagnoses (eg: Anthrax) Creates more jobs and improves the economy.
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Nanotechnology has made it possible for a single chip to possess more than million features with its detection abilities than that of conventional methods. Nanotechnology has made biochips more applicable for commercialization purpose where biochips could be implanted inside body to dynamically transmit the information and monitor any biological changes in vivo. There has been significant progress on applications of biochips such as DNA chips, protein chips, and carbohydrate chips, and MEMS/NEMS in the field of medical nanotechnology. One could believe that when fused together, biochips and nanotechnology will endlessly bring scientists to newer and promising researching aspects.
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Biochips is a very broad field Many different types of biochips Biochips is going to set the new trend in Medicine Still in research phase, but soon will be commercially used
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