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Stem cells: disease models and therapeutics
Want to talk about Brain Reconstruction, and whether it is either possible or desirable. Two contexts: the unmet medical need associated with Brain Damage. Enhancement. There is an assumption in much of the literature associated with Human Enhancement that it is possible to take damaged brains and not only restore them, but to make them better. This is seen as a goal, by many such as John Harris, or as an ethical problem associated with regenerative therapies in the brain, such as Duggan et al. Whether such enhancement is a goal or a problem, the question I want to address is: is it achievable, and is it necessary? Jack Price Centre for the Cellular Basis of Behaviour Institute of Psychiatry, KCL. 1
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Jack Price Centre for the Cellular Basis of Behaviour
Opportunities Therapy Mechanisms of Repair Cellular Models Disease Mechanisms Want to talk about Brain Reconstruction, and whether it is either possible or desirable. Two contexts: the unmet medical need associated with Brain Damage. Enhancement. There is an assumption in much of the literature associated with Human Enhancement that it is possible to take damaged brains and not only restore them, but to make them better. This is seen as a goal, by many such as John Harris, or as an ethical problem associated with regenerative therapies in the brain, such as Duggan et al. Whether such enhancement is a goal or a problem, the question I want to address is: is it achievable, and is it necessary? Jack Price Centre for the Cellular Basis of Behaviour Institute of Psychiatry, KCL. 2
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Stroke Human Neural stem cells
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iPS cells from human keratinocytes
biopsy keratinocytes piggybac iPS cells Neural progenitors Neurons Cellular Assays Oct4 SHANK3 domain structure Deleted region: exons
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EC Aaron Jeffries Dafe Uwanogho Graham Cocks Zahra Hassani Leo Perfect
The Charles Wolfson Charitable Trust Aaron Jeffries Dafe Uwanogho Graham Cocks Zahra Hassani Leo Perfect Mike Modo Ellen Bible Nataliya Gorenkova Eva Syková Pavla Jendelová Govindan Dayanithi Sandrine Thuret Nick Bray Carmine Pariante Jon Mill Leo Schzlkwyk
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