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DEANNA DAILEY DR. CHAN’S HUMAN PHYS G BLOCK Why do some allergens effect different people in different ways?

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Presentation on theme: "DEANNA DAILEY DR. CHAN’S HUMAN PHYS G BLOCK Why do some allergens effect different people in different ways?"— Presentation transcript:

1 DEANNA DAILEY DR. CHAN’S HUMAN PHYS G BLOCK Why do some allergens effect different people in different ways?

2 What is an allergic reaction? An allergic response is when an antibody binds to and antigen and irritation occurs. Types of reactions:  Rash or hives  Swelling: epically of the lips, tongue, throat, face  Dizziness  Nausea/ diarrhea  Anaphylaxis http://www.walgreens.com/marketing/library/contents.jsp?do ctype=2&docid=8700 https://mnfoodallergies.wordpress.com/tag/food-allergy-reactions/

3 Steps to an allergic reaction 1. The antigen enters the body 2. Triggered B-cells to produce IgE antibodies 3. These antibodies target the specific allergen 4. This releases histamine to battle the allergen causing a reaction. Depending on how sensitized, the genes of the person, or how much histamine is released, the person can have a mild or major reaction. http://www.etetens.com/bi obili/biocourse/allergies.ht ml

4 Why are there different effects? Genes  MHC  Controlled by different genes and they have many different variations.  Just because you are disposed to it, does not mean that you will have the allergy. Socioeconomic background  Immunity towards allergens was a defense mechanism  Variation in total and specific IgE: effects of ethnicity and socioeconomic status Exposure  The more you are exposed, the worse the symptoms can be.

5 Works Cited Celedon, J. C. "Variation in Total and Specific IgE: Effects of Ethnicity and Socioeconomic Status." PubMed.gov (2005): n. pag. Web. 15 Jan. 2015..http://www.ncbi.nlm.nih.gov/pubmed/15805994 "Allergic Reactions: MedlinePlus Medical Encyclopedia." U.S National Library of Medicine. Ed. Stuart I. Henochowicz, David Zieve, and Isla Ogilvie. U.S. National Library of Medicine, 10 May 2014. Web. 23 Jan. 2015..http://www.nlm.nih.gov/medlineplus/ency/article/000005.htm Asthma and Allergy Foundation of America. "IGE'S ROLE IN ALLERGIC ASTHMA." Asthma and Allergy Foundation of America. Asthma and Allergy Foundation of America, 2005. Web. 25 Jan. 2015..http://www.aafa.org/display.cfm?id=8&sub=16&cont=54 Asthma and Allergy Foundation of America. "Asthma and Allergy Foundation of America - Information About Asthma, Allergies, Food Allergies and More!" WHAT CAUSES ALLERGIES. Asthma and Allergy Foundation of America, 2011. Web. 25 Jan. 2015..http://www.aafa.org/display.cfm?id=9&cont=79

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